International Journal of Clinical Research

Objective To clarify the value of lithium carbonate combined with olanzapine treatment in patients with bipolar disorder. Methods 69 patients with clinical comprehensive diagnosis of bipolar disorder in the hospital from July 2024 to July 2025 were used as the test observation objects. The test groups were carried out according to the randomized digital table method, including the control group (34 cases) and the observation group (35 cases). The treatment modes of different groups were carried out by conventional means and lithium carbonate combined with olanzapine methods, and the results were analyzed and compared. Results Compared with the data between groups, the results between the subjects compared after treatment showed a significant difference of P<0.05. In terms of metabolic indicators, the observation group was more normal, and manic and depressive symptoms showed that the observation group was lighter. Conclusion The treatment of lithium carbonate combined with olanzapine in patients with bipolar disorder is of great significance for alleviating clinical symptoms and helps to stabilize glycolipid metabolism indicators.

Bipolar disorder; Lithium carbonate; Olanzapine; Metabolic indicators