International Journal of Clinical Research

Objective To investigate the clinical efficacy and safety of ERCP/EST combined with laparoscopic cholecystectomy (LC) in the treatment of common bile duct stones with acute cholangitis and gallstones. Methods From February 2020 to January 2025, 76 patients with common bile duct stones accompanied by acute cholangitis and gallstones were selected and divided into an observation group (n=38) and a control group (n=38) according to different surgical plans. The observation group received a one-stage treatment plan of ERCP/EST combined with laparoscopic cholecystectomy, while the control group received a one-stage treatment plan of laparoscopic cholecystectomy combined with common bile duct exploration and stone extraction (LCBDE). The treatment effects of the two groups were compared. Results The observation group had less intraoperative bleeding, shorter postoperative anal exhaust time, and shorter postoperative hospitalization time, which was better than the control group (P<0.05). There was no significant difference in the one-time stone clearance rate between the two groups (P>0.05), but the total incidence of postoperative complications in the observation group was significantly lower than that in the control group (P<0.05). The postoperative observation group showed a more significant decrease in white blood cell count (WBC) and C-reactive protein (CRP) levels (P<0.05). Conclusion For patients with common bile duct stones accompanied by acute cholangitis and gallstones, the staged treatment plan of ERCP/EST combined with LC is more effective and worthy of clinical promotion.

ERCP/EST; Laparoscopic cholecystectomy; Common bile duct stones; Acute cholangitis; Gallbladder stones