齐拉西酮联合心理干预在青少年精神分裂症中的应用效果及对预后的影响研究

Study on the effect of ziprasidone combined with psychological intervention in the treatment of adolescent schizophrenia

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2017, 44(5)
作者
作者单位

湖北省恩施州精神卫生中心 ;

摘要
【摘要】目的:探讨齐拉西酮联合心理干预在青少年精神分裂症中的应用及对预后的影响。方法:取2014年1月-2016年12月医院收治青少年精神分裂症患者90例,随机数字法分为对照组(n=45)和观察组(n=45)。对照组采用齐拉西酮治疗,观察组联合心理干预治疗,采用PANSS对2组治疗效果进行评估,比较2组临床疗效及对预后的影响。结果:观察组治疗后有效率为94.1%,对照组为67.6%,2组有效率比较差异有统计学意义(P<0.05);两组治疗前PANSS评分比较差异无统计学意义(P>0.05),观察组治疗后阳性量表、阴性量表、一般病理及量表总分,低于对照组(P<0.05)。结论:青少年精神分裂症患者在齐拉西酮基础上联合心理干预治疗效果理想,能降低患者心理波动,改善患者预后,值得推广应用。
Abstract
【Abstract】 Objective: To investigate the effect of ziprasidone combined with psychological intervention in the treatment of adolescent schizophrenia. Methods: 90 patients with schizophrenia were randomly divided into control group (n=45) and observation group (n=45) in our hospital from January 2014 to -2016 in December. The control group was treated with ziprasidone, the observation group was treated with psychological intervention, PANSS was used to evaluate the therapeutic effects of the 2 groups, and the clinical efficacy and prognosis were compared between the 2 groups. Results: the observation group after treatment was 94.1%, 67.6% in the control group, the 2 groups were statistically significant efficiency difference (P < 0.05); the PANSS score had no significant difference between the two groups before treatment (P > 0.05), the observation group after treatment of positive and negative scale, scale and quantity of general pathology the total score, lower than the control group (P < 0.05). Conclusion: the effect of psychological intervention in the treatment of schizophrenia in adolescents with schizophrenia is ideal, which can reduce the patients psychological fluctuations and improve the prognosis of patients, which is worthy of popularization and application.
关键词
【关键词】齐拉西酮;心理干预;青少年精神分裂症;效果;预后
KeyWord
【keyword】ziprasidone; psychological intervention; adolescent schizophrenia; effect; prognosis
基金项目
页码 794-796
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杨玲*,付艳梅,曹宏波, 张莉琳. 齐拉西酮联合心理干预在青少年精神分裂症中的应用效果及对预后的影响研究 [J]. 国际精神病学杂志. 2017; 44; (5). 794 - 796.

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