International Journal of Nursing Research

Objective To compare the effects of high-flow nasal humidified oxygen therapy (HFNC) and traditional mask oxygen inhalation on perioperative circulatory function during surgical procedures under intravenous general anesthesia. Methods A comparative clinical study was conducted in 61 patients undergoing non-intubated intravenous anesthesia between January 2023 and December 2023. Preoperatively, patients were randomly assigned to a control group (31 patients) who received traditional mask oxygen inhalation, while an observation group (30 patients) received HFNC oxygen inhalation. Differences in perioperative circulatory function parameters (mean arterial pressure (MAP), heart rate (HR), and blood oxygen saturation (SpO2)), surgical duration, postoperative recovery time, intraoperative anesthetic dosage, and the incidence of adverse events related to oxygen inhalation were compared between the two groups. Results No statistically significant differences were found in the preoperative general data between the two groups (P>0.05). In terms of circulatory function, the heart rate (HR) in the observation group was significantly lower immediately after lesion resection and immediately after surgery than in the control group (both P<0.05), and the blood oxygen saturation (SpO₂) immediately after surgery was significantly higher than that in the control group (P<0.05). However, no statistically significant differences were found in mean arterial pressure (MAP) at any time point between the two groups (both P>0.05). The postoperative recovery time in the observation group was significantly shorter than that in the control group [(3.62±0.98) min vs (4.45±1.04) min, P=0.002]. However, no statistically significant differences were found in the operative time, propofol dosage, and sufentanil dosage between the two groups (all P>0.05). The overall incidence of adverse events related to oxygen support, such as hypoxemia, was not statistically significantly different between the two groups [16.67% (5/30) vs 12.90% (4/31), P = 0.679]. Conclusions Both HFNC and face mask oxygen inhalation can be used for non-intubated intravenous anesthesia surgery. However, in terms of intraoperative efficacy, HFNC has certain advantages in improving patient oxygenation and circulatory system stability and can be used as appropriate.

Non-intubated intravenous anesthesia; High-flow nasal humidified oxygen therapy; Face mask oxygen inhalation; Circulatory system