帕金森病患者情绪与认知功能研究

The research of emotions and cognitive function in patients with Parkinsons Disease.

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2018, 45(6)
作者
作者单位

聊城市第四人民医院 ;
聊城市第四人民医院精神科 ;

摘要
探讨慢性帕金森病(Parkinsons Disease,PD)患者与健康对照组(health controls,HC)的情绪与认知功能的差异。 方法 将87例PD患者及90例HC被试;情绪状况水平采用焦虑症状自评量表(Self-Rating Anxiety Scale,SAS)和抑郁症状自评量表(Self-rating depression scale,SDS)进行评估;采用词汇流畅性、数字广度、威斯康辛卡片分类测试(Wisconsin Card Sorting Test,WCST)评估两组认知功能差异。 结果 PD组[(47.38±10.90)分,(49.97±10.77)分]在SAS、SDS得分高于HC组[(43.90±11.15)分,(45.17±12.08)分],差异有统计学意义(t=-2.099,P=0.037;t=-2.787,P=0.006)。相较于HC组[(66.04±4.71)次],PD组[(63.40±5.69)次]在WCST正确应答数较差,差异有统计学意义(t=3.369,P=0.001),PD组SAS量表得分与WCST中正确应答数呈负相关(r=-0.242,P=0.024)。结论 PD患者存在情绪和认知功能的异常,情绪异常对认知功能有消极影响。
Abstract
Objective To explore the different of emotions and cognitive function between primary insomnia(PI) patients and health controls(HC). Methods A total of 87 PD patients were compared with matched 90 HC. Emotions of all the subjects were assessed by Self-Rating Anxiety Scale(SAS)、Self-Rating Depression Scale (SDS);Cognitive function of all the subjects were assessed by verbal fluency、digit span、Wisconsin Card Sorting Test. Results The score of SAS、SDS in PD group were higher than the HC group[(47.38±10.90) score vs (43.90±11.15) score,t=-2.099,P=0.037; (49.97±10.77) score vs (45.17±12.08) score,t=-2.787,P=0.006]. Compared with HC group [(66.04±4.71)time],PD group[(63.40±5.69) time]showed signiflcantly impaired in performance of replies correct number of WCST (t=3.369,P=0.001), The score of SAS in PD group was negatively correlated with replies correct number of WCST(r= -0.242, P= 0.024).Conclusion The studies suggest prevalence of emotions and cognitive function problems in PD patients,Emotional abnormalities have a negative effect on cognitive function.
关键词
帕金森病;情绪;认知
KeyWord
Parkinson’s disease;emotion ;cognitive;
基金项目
页码 1074-1076
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赵长印,张君*. 帕金森病患者情绪与认知功能研究 [J]. 国际精神病学杂志. 2018; 45; (6). 1074 - 1076.

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