脑源性神经营养因子在急性冠脉综合征合并抑郁症患者中的研究进展
The progress in the study of BDNF in patients with acute coronary syndrome complicated with depression
ES评分 0
| DOI |
| 刊名 |
Journal of International Psychiatry
|
| 年，卷(期) |
2019, 46(1) |
| 作者 |
|
| 作者单位 |
重庆医科大学附属第一医院 ;
|
| 摘要 |
随着心血管疾病及精神疾病发病率逐年上升，急性冠脉综合征（acute coronary syndrome, ACS）合并抑郁症人群逐年增加，躯体疾病与精神障碍共存，严重影响患者的生活质量及预后，而抑郁症发病隐匿，临床表现多样，不利于早期发现，找到ACS合并抑郁症患者的生物学标志物可帮助早期干预并改善患者预后。脑源性神经营养因子（Brain-Derived Neurotrophic Factor，BDNF）为神经营养因子家族中一员，可调节血管及神经元的生成、存活和维持，研究发现BDNF与ACS及抑郁症相互关联，有望成为ACS合并抑郁症的生物学标志物，现就BDNF在ACS合并抑郁症患者中的研究进展做一综述。
|
| Abstract |
With the increasing incidence of cardiovascular diseases and mental diseases, the population of acute coronary syndrome (ACS) with depression is increasing year by year. Somatic diseases and mental disorders coexist, which seriously affects the quality of life and prognosis of patients. The onset of depression and multiple clinical manifestations are not conducive to early detection. Finding biomarkers in ACS patients with depression can help early intervention and improve the prognosis of patients. Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophic factor family and participates in vascular and neuronal angiogenesis、survival and maintenance. It has been found that BDNF is associated with ACS and depression. It is expected to become a biological marker of ACS with depression. Now we review the research progress of BDNF in ACS patients with depression.
|
| 关键词 |
脑源性神经营养因子；急性冠脉综合征；抑郁症
|
| KeyWord |
BDNF; Acute coronary syndrome; Depression
|
| 基金项目 |
|
| 页码 |
46-49 |
王靖,高凌云*.
脑源性神经营养因子在急性冠脉综合征合并抑郁症患者中的研究进展 [J].
国际精神病学杂志.
2019; 46; (1).
46 - 49.