前颞叶切除术治疗TLE患者对认知记忆和睡眠质量的影响

Effect of anterior temporal lobectomy on TLE patients cognitive memory and sleep quality

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2019, 46(4)
作者
作者单位

河南郑州颐和医院神经外科 ;

摘要
目的探讨前颞叶切除术治疗颞叶癫痫(TLE)对患者认知记忆功能、睡眠质量的影响。方法选取我院2013年2月至2018年4月收治的手术治疗的60例TLE患者进行回顾性分析,其中采取海马横切术治疗的30例(A组)、30例采用前颞叶切除术(B组),对比两组患者术前、术后2周的认知记忆功能、睡眠质量变化。结果术前,A组和B组患者的PIQ、VIQ、FIQ、MQ评分差异不具有统计学意义(P>0.05);术后2周,A组患者的PIQ、VIQ、FIQ、MQ评分均高于B组(P<0.05);术前,A组和B组患者的主观睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍、PSQI评分差异不具有统计学意义(P>0.05);术后2周,A组患者的主观睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍、PSQI评分均低于B组(P<0.05)。结论TLE患者采用前颞叶切除术治疗较海马横切术治疗对认知、记忆功能的影响更严重,患者术后的睡眠质量较差。
Abstract
Objective To investigate the effect of temporal lobe resection for temporal lobe epilepsy (TLE) on cognitive memory function and sleep quality in patients. Methods A retrospective analysis was performed on 60 TLE patients who underwent surgical treatment from February 2013 to April 2018 in our hospital. Thirty patients (Group A) and 30 patients were treated with anterior temporal lobectomy. Group B), comparing the cognitive memory function and sleep quality changes between the two groups before and 2 weeks after surgery. Results Before surgery, the differences in PIQ, VIQ, FIQ, and MQ scores between group A and group B were not statistically significant (P>0.05); the PIQ, VIQ, FIQ, and MQ scores of group A were higher than those of group A 2 weeks after surgery. In group B (P<0.05), there was no significant difference in subjective sleep quality, sleep time, sleep time, sleep efficiency, sleep disturbance, hypnotic drugs, daytime dysfunction, and PSQI score between preoperative and postoperative groups A and B. (P>0.05); At 2 weeks after operation, subjective sleep quality, sleep time, sleep time, sleep efficiency, sleep disturbances, hypnotic drugs, daytime dysfunction, PSQI scores in group A were all lower than those in group B (P<0.05). Conclusion The treatment of TLE patients with anterior temporal lobe resection compared with hippocampal transverse resection has a more severe impact on cognition and memory function, and the degree of sleep disturbance is more serious in patients.
关键词
前颞叶切除术;颞叶癫痫;认知记忆功能;睡眠质量
KeyWord
Pre-temporal lobectomy; temporal lobe epilepsy; cognitive and memory function; sleep quality
基金项目
页码 648-651
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王学忠*. 前颞叶切除术治疗TLE患者对认知记忆和睡眠质量的影响 [J]. 国际精神病学杂志. 2019; 46; (4). 648 - 651.

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