| Abstract |
To investigate the clinical incidence, distribution and related risk factors of cerebral microbleeds in patients with acute cerebral infarction.Methods: A total of 102 patients with acute cerebral infarction who were treated in our hospital from August 2015 to August 2017 were enrolled. The patients were divided into cerebral microbleeds and non-brain microbleeds by imaging examination.Compare the general data,HAMD score, blood biochemical indicators and imaging findings of the two groups, and record the number and distribution of brain microbleeds.Single factor and multivariate logistic regression were used to analyze the clinical incidence and related risk factors of cerebral microbleeds in patients with acute cerebral infarction.ResultsS: Through the head MRI scan, 59 patients with acute cerebral infarction had cerebral microbleeds in the brain, and 43 patients with acute cerebral infarction did not find cerebral microbleeds in the brain. The clinical incidence rate was 57.84%. A total of 514 brain microbleeds were scanned, with an average of 8.71. Mainly distributed in: the lesions located in the basal ganglia / thalamus area of 24 patients, a total of 203 lesions (39.49%), the largest number; lesions located in the brain lobe - cortex 20 patients, 183 lesions (28.60%); lesions There were 15 patients in the lower part of the area, with a total of 128 lesions (24.90%). The HAMD score of the cerebral microbleeds group was (18.15±4.37), which was higher than that of the non-brain microbleeding group (6.29±3.42), and the difference was statistically significant (P<0.05). One-way logistic regression analysis showed that there was a correlation between age, hypertension, stroke, leukoaraiosis, cerebral infarction and cerebral microhemorrhage in patients with acute cerebral infarction. There was no correlation between blood biochemical parameters and cerebral microbleeds in patients with acute cerebral infarction. After multivariate logistic regression analysis, age, hypertension, leukoaraiosis, and cerebral infarction were independent risk factors for cerebral microbleeds in patients with acute cerebral infarction.Conclusion: The clinical incidence of cerebral microbleeds in patients with acute cerebral infarction is high. The lesions are mainly distributed in the basal ganglia/thalamic area. Age, hypertension, leukoaraiosis and cerebral infarction are independent risk factors for cerebral microbleeds in patients with acute cerebral infarction. The incidence of depression in patients with cerebral microbleeds was higher than that in patients without cerebral microbleeds.
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