度洛西汀联合认知行为干预治疗抑郁症的临床效果及对患者自杀意念的影响研究
Clinical effect of duloxetine combined with cognitive behavioral intervention on depression and its effect on suicidal ideation
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(1) |
| 作者 |
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| 作者单位 |
山东省聊城市第四人民医院 ;
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| 摘要 |
目的：分析度洛西汀联合认知行为干预治疗抑郁症的临床效果及对患者自杀意念的影响。方法：抽取于本院接受治疗的100例抑郁症患者做分组调查，依据治疗方案的不同做分组，50例度洛西汀治疗患者为对照组，另外50例度洛西汀联合认知行为干预治疗患者为观察组，对比两组治疗效果。结果：干预之前，两组患者的HAMD评分并未呈现出显著差异，但经不同干预治疗后，观察组患者干预后2周到7周期HAMD评分均明显小于对照组患者（P＜0.05），干预前两组患者各项QSA指标评分均无明显差异，但经不同方案干预后，观察组患者QSA各项指标评分均明显大于对照组（P＜0.05），干预前两组患者的认知障碍因子自杀项评分并无明显差异，但经不同方案干预后，观察组患者干预后2周到8周的认知障碍因子自杀项评分均明显低于对照组患者（P＜0.05）。结论:抑郁症属于心境障碍的主要类型之一，为此，在治疗期间还需要关注到患者心理状态的变化，本次研究证实，在常规药物治疗的基础上参与认知行为干预，能够进一步影响到患者对自杀行为的认知，于控制患者自杀意念的基础上，缓解患者的抑郁状态。
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| Abstract |
To analyze the clinical effects of duloxetine combined with cognitive behavioral intervention in the treatment of depression and its impact on suicidal ideation. Methods: 100 patients with depression who were treated in our hospital were divided into groups according to different treatment options. 50 patients treated with duloxetine were used as control group and 50 patients with duloxetine combined with cognitive behavioral intervention. The treated patients were the observation group, and the treatment effects of the two groups were compared. RESULTS: Before the intervention, the HAMD scores of the two groups did not show significant differences. However, after different interventions, the HAMD scores of the observation group from 2 weeks to 7 days after intervention were significantly lower than those of the control group (P<0.05). There were no significant differences in the scores of QSA indicators between the two groups. However, after intervention with different regimens, the scores of QSA indicators in the observation group were significantly higher than those in the control group (P<0.05). The cognitive impairment factor suicide in the two groups before intervention. There was no significant difference in the scores. However, after intervention with different regimens, the scores of cognitive impairment factors in the observation group from 2 weeks to 8 weeks after intervention were significantly lower than those in the control group (P<0.05). Conclusion: Depression is one of the main types of mood disorders. For this reason, it is necessary to pay attention to the changes in the patients psychological state during the treatment. This study confirms that participation in cognitive behavioral intervention based on conventional drug therapy can further influence. To the patients cognition of suicidal behavior, on the basis of controlling the suicidal ideation of the patient, the depression state of the patient is alleviated.
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| 关键词 |
度洛西汀；认知行为；抑郁症；自杀意念
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| KeyWord |
duloxetine; cognitive behavior; depression; suicidal ideation
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| 基金项目 |
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| 页码 |
74-77 |
哈保卫*,杨拥军.
度洛西汀联合认知行为干预治疗抑郁症的临床效果及对患者自杀意念的影响研究 [J].
国际精神病学杂志.
2020; 47; (1).
74 - 77.