重复经颅磁刺激应用于脑卒中后癫痫合并焦虑抑郁共病患者的效果观察
Effect of repeated transcranial magnetic stimulation on post-stroke epilepsy patients with anxiety and depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2019, 46(4) |
| 作者 |
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| 作者单位 |
濮阳市油田总医院全科医学科 ;
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| 摘要 |
观察脑卒中后癫痫合并焦虑抑郁共病患者应用重复经颅磁刺激治疗后效果。方法 将93例脑卒中后癫痫合并焦虑抑郁共病患者随机分组，对照组46例予常规西医治疗，观察组47例联合重复经颅磁刺激，对比两组患者焦虑抑郁情绪、神经功能、神经递质、血液流变学变化及不良事件发生率。结果 观察组治疗后NE水平高于对照组，HAMD、HAMA、NIHSS评分及Fib、PAl、LSV、HSV、ηs、5-HT水平均低于对照组（P<0.05）；不良事件发生率低于对照组（P>0.05）。结论 重复经颅磁刺激能够有效改善脑卒中后癫痫合并焦虑抑郁共病患者神经递质及血液流变学水平，其机制与调节大脑皮质兴奋性有关。
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| Abstract |
Objective To observe the effect of repeated transcranial magnetic stimulation in epilepsy patients with anxiety-depression after stroke. Methods Randomly devided 93 post-stroke epilepsy patients with anxiety-depression into 2 groups. 46 cases in control group given conventional Western medicine. 47 cases in observation group added repetitive transcranial magnetic stimulation.Compered the depression, neurological function, neurotransmitter, hemorheological changes and adverse events. Results The NE level in observation group was higher than control group. The HAMD, HAMA, NIHSS scores and Fib, PAl, LSV, HSV, ηs and 5-HT levels were lower than control group (P<0.05). The adverse events rate was lower than control group(P>0.05). Conclusion Repetitive transcranial magnetic stimulation can improve neurotransmitter and hemorheology in post-stroke epilepsy patients with anxiety-depression. The mechanism is related to the regulation of cerebral cortex excitability.
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| 关键词 |
重复经颅磁刺激；脑卒中；焦虑抑郁共病
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| KeyWord |
repetitive transcranial magnetic stimulation; stroke; anxiety and depression comorbidity
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| 基金项目 |
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| 页码 |
693-695 |
肖夏*.
重复经颅磁刺激应用于脑卒中后癫痫合并焦虑抑郁共病患者的效果观察 [J].
国际精神病学杂志.
2019; 46; (4).
693 - 695.