舒肝解郁胶囊联合复方消化酶对功能性消化不良患者疗效及焦虑抑郁情绪的影响
Effect of Shugan Jieyu Capsule Combined with Compound Digestive Enzyme on the Efficacy and Anxiety and Depression of Patients with Functional Dyspepsia
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| DOI |
| 刊名 |
Journal of International Psychiatry
|
| 年，卷(期) |
2019, 46(3) |
| 作者 |
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| 作者单位 |
安阳市中医院肝胆脾胃科 ;
|
| 摘要 |
分析功能性消化不良患者应用舒肝解郁胶囊联合复方消化酶治疗后效果。方法 将我院95例功能性消化不良患者采用随机数字表法分组，对照组47例给予复方消化酶口服治疗，观察组48例联合舒肝解郁胶囊治疗，对比两组患者治疗后5-羟色胺（5-HT）、一氧化氮合酶（NOS）水平、焦虑抑郁评分、症状积分、临床疗效、不良反应及复发率。结果 观察组治疗后NOS水平、HAMA、HAMD评分、症状积分及复发率均低于对照组，5-HT水平及总有效率均高于对照组（P<0.05），不良反应发生率低于对照组（P>0.05）。结论 舒肝解郁胶囊联合复方消化酶能够有效改善功能性消化不良患者焦虑抑郁情绪，消除症状体征，复发率低，其机制与调节调节NOS、5-HT水平，改善胃动力有关。
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| Abstract |
Objective To analyze the effect of Shugan Jieyu Capsule combined with compound digestive enzyme in patients with functional dyspepsia. Methods 95 patients with functional dyspepsia were randomly divided into two groups. The control group was treated with compound digestive enzymes in 47 cases, and the observation group was treated with Shugan Jieyu capsules. The two groups were treated with serotonin. (5-HT), nitric oxide synthase (NOS) levels, anxiety and depression scores, symptom scores, clinical efficacy, adverse reactions, and recurrence rates. Results The NOS level, HAMA, HAMD score, symptom score and recurrence rate of the observation group were lower than those of the control group. The 5-HT level and total effective rate were higher than the control group (P<0.05). The incidence of adverse reactions was lower than that of the control group. Group (P>0.05). Conclusion Shugan Jieyu Capsule combined with compound digestive enzyme can effectively improve the anxiety and depression of patients with functional dyspepsia, eliminate symptoms and signs, and have a low recurrence rate. The mechanism is related to the regulation of NOS and 5-HT levels and improvement of gastric motility.
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| 关键词 |
舒肝解郁胶囊；复方消化酶；功能性消化不良；焦虑；抑郁
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| KeyWord |
Shugan Jieyu capsule; compound digestive enzyme; functional dyspepsia; anxiety; depression
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| 基金项目 |
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| 页码 |
539-541 |
王萍*.
舒肝解郁胶囊联合复方消化酶对功能性消化不良患者疗效及焦虑抑郁情绪的影响 [J].
国际精神病学杂志.
2019; 46; (3).
539 - 541.