文拉法辛联合团体人际心理疗法对社交恐惧症患者疗效及自我效能感、HAMA评分的影响
Effect of Venlafaxine Combined with Group Interpersonal Psychotherapy on the Efficacy, Self-Efficacy and HAMA Score of Patients with Social Phobia
ES评分 0
| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2019, 46(5) |
| 作者 |
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| 作者单位 |
山东省临沂市精神卫生中心 ;
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| 摘要 |
目的：探讨文拉法辛联合团体人际心理疗法对社交恐惧症患者的治疗效果极其对患者一般自我效能感量表（general self-efficacy scale, GSES）、汉密尔顿焦虑量表（Hamilton Anxiety Scale,HAMA）评分的影响。方法：选择2016年8月-2018年12月在我院接受治疗和76例社交恐惧症患者作为研究对象，根据随机性原则将其随机分为对照组38例和联合组38例。所有患者均给予文拉法辛治疗，联合组患者同时接受团体人际心理治疗。比较两组患者的治疗效果、不良反应发生率及治疗前后HAMA评分、社交回避及苦恼量表（social avoidance and sistress scale,SAD）评分和GSES评分变化情况。结果：（1）治疗12周后，联合组总有效率为94.74%，对照组为68.42%，前者显著高于后者（X²=8.756，P=0.003）；治疗过程中联合组头晕、便秘和口干的发病率均显著低于对照组（P＜0.05）。（2）治疗前两组患者HAMA、GSES评分比较差异无统计学意义（P＞0.05），治疗后6周和12周两组患者的HAMA评分均显著降低，且联合组治疗后HAMA评分均显著低于对照组（P＜0.05）；治疗6周时对照组GSES评分较治疗前无明显变化（P＞0.05），治疗12周时显著提高（P＜0.05），联合组患者6周和12周时GSES评分较治疗前均显著升高，且均明显高于对照组（P＜0.05）。（3）治疗前两组患者的SAD总分和各维度评分比较差异均无统计学意义（P＞0.05）；治疗6周时，对照组SAD总分和社交回避、内心苦恼两个维度评分较治疗前无显著变化，差异比较无统计学差异（P＞0.05），联合组SAD总分和两个维度评分较治疗前均显著降低，且显著低于对照组（P＜0.05）；治疗12周时，对照组SAD总分和社交回避、内心苦恼两个维度评分较治疗前显著降低，联合组较治疗前也显著降低，且显著低于对照组（P＜0.05）。结论：团体人际心理疗法联合文拉法辛对社交恐惧症患者相比单纯的药物治疗效果更为显著，二者相互补充能显著改善患者在日常生活和社交活动中所表现出的焦虑、担忧和恐惧等症状，还有助于提高患者的自我效能感，而且不良反应少，值得临床应用。
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| Abstract |
Objective: To explore the effect of venlafaxine combined with group interpersonal psychotherapy on social phobia patients and its influence on general self-efficacy scale (GSES) and Hamilton Anxiety Scale (HAMA). Methods: 76 patients with social phobia were randomly divided into control group (38 cases) and combination group (38 cases). All patients were treated with venlafaxine, while the combined group received group interpersonal psychotherapy. The therapeutic effect, incidence of adverse reactions and changes of HAMA score, social avoidance and sistress scale (SAD) score and GSES score before and after treatment were compared between the two groups. Results: (1) The total effective rate was 94.74% in the combined group and 68.42% in the control group. The former was significantly higher than the latter (X²=8.756, P=0.003); the incidence of dizziness, constipation and xerostomia in the combined group were significantly lower than those in the control group (P<0.05). (2) The HAMA scores of the two groups were significantly decreased after 6 and 12 weeks of treatment, and the HAMA scores of the combined group were significantly lower than those of the control group after treatment (P < 0.05). At 6 and 12 weeks, the GSES score of the combined group was significantly higher than that of the control group (P < 0.05). (3) At 6 weeks of treatment, there was no significant difference in SAD total score and social avoidance and inner distress between the control group and before treatment (P > 0.05). SAD total score and two dimension score in the combined group were significantly lower than before treatment. In the control group (P < 0.05), at 12 weeks of treatment, the total SAD score, social avoidance and inner distress scores of the control group were significantly lower than those before treatment, and the combined group was significantly lower than those before treatment, and significantly lower than those of the control group (P < 0.05). Conclusion: Group interpersonal psychotherapy combined with venlafaxine is more effective than drugs alone in the treatment of social phobia. Their complementation can significantly improve the symptoms of anxiety, anxiety and fear in daily life and social activities, and also help to improve the self-efficacy of patients with social phobia, with fewer adverse reactions, which is worthy of clinical application.
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| 关键词 |
社交恐惧症；文拉法辛；团体人际心理治疗；社交回避；社交苦恼
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| KeyWord |
Social phobia; Venlafaxine; Group interpersonal psychotherapy; Social avoidance; Social distress
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| 基金项目 |
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| 页码 |
863-866 |
刘振东*.
文拉法辛联合团体人际心理疗法对社交恐惧症患者疗效及自我效能感、HAMA评分的影响 [J].
国际精神病学杂志.
2019; 46; (5).
863 - 866.