单次亚麻醉剂量氯胺酮对结直肠肿瘤患者术后焦虑、抑郁等情绪反应的影响
Effects of single subanesthetic dose of ketamine on post-operative anxiety and depression in patients with colorectal cancer
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(1) |
| 作者 |
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| 作者单位 |
郑州大学附属肿瘤医院麻醉科 ;
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| 摘要 |
目的：评价单次亚麻醉剂量氯胺酮对结直肠肿瘤患者术后焦虑、抑郁等情绪反应的影响，便于为临床应用提供依据。方法：根据纳入标准与排除标准选取我院2017年3月-2019年3月期间收治的60例结直肠癌患者。使用生理盐水的30例为对照组，使用单次亚麻醉剂量氯胺酮的30例为观察组，对比两组患者术前、术后焦虑和抑郁评分；麻醉时间、拔管时间以及术后VAS评分。结果：观察组术后焦虑、抑郁评分小于对照组，观察组麻醉时间、拔管以及术后24h的VAS评分均小于对照组，各项指标组间对比有显著差异（P＜0.05）。结论：单次亚麻醉剂量氯胺酮在结直肠肿瘤患者术后焦虑抑郁改善以及手术指标优化方面均有重要应用价值，临床可借鉴与推广应用。
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| Abstract |
Objective: To evaluate the effect of ketamine on post-operative anxiety and depression in patients with colorectal cancer, so as to provide evidence for clinical application. Methods: According to the inclusion and exclusion criteria, 60 patients with colorectal cancer were selected from March 2017 to March 2019 in our hospital. The anxiety and depression scores, anesthesia time, extubation time and VAS scores were compared between the two groups. Results: The scores of anxiety and depression in the observation group were lower than those in the control group. The VAS scores in the observation group at anesthesia time, extubation and 24 hours after operation were lower than those in the control group. There were significant differences in the indexes between the two groups (P < 0.05). CONCLUSION: Single subanesthesia dose ketamine has important application value in improving anxiety and depression and optimizing surgical index in patients with colorectal cancer after operation. It can be used for reference and popularization in clinic.
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| 关键词 |
单次亚麻醉剂量；氯胺酮；结直肠肿瘤；术后焦虑；抑郁；情绪反应
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| KeyWord |
Single subanesthetic dose; Ketamine; Colorectal neoplasms; Postoperative anxiety; Depression; Emotional response
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| 基金项目 |
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| 页码 |
110-113 |
王根生*.
单次亚麻醉剂量氯胺酮对结直肠肿瘤患者术后焦虑、抑郁等情绪反应的影响 [J].
国际精神病学杂志.
2020; 47; (1).
110 - 113.