全身麻醉、椎管内麻醉应用于骨科手术患者(高龄)对其术后精神状态、认知功能的影响分析
Comparison of anesthetic effects of remifentanil and fentanyl on schizophrenic patients
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(1) |
| 作者 |
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| 作者单位 |
南阳市中心医院麻醉科 ;
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| 摘要 |
目的：比较雷米芬太尼与芬太尼应用在精神分裂症患者术中的麻醉效果。方法：研究资料均为本院于2015年9月至2018年9月期间收治的行手术治疗精神分裂症患者100例，依据麻醉方案分组各50例，对照组术中为芬太尼联合丙泊酚麻醉，观察组为雷米芬太尼联合丙泊酚麻醉，记录两组患者麻醉不同时间点心率、血压变化，并进行比较。结果：两组患者麻醉前和麻醉后1min心率比较无统计学意义，P＜0.05；麻醉后不同阶段观察组心率出现波动，其中插管后1min、切皮时显著低于对照组，而手术结束时及睁眼时显著高于对照组，P＜0.05；麻醉前、手术结束时及睁眼时两组患者收缩压、舒展压比较无统计学意义，P＞0.05；麻醉后1min观察组收缩压、舒展压显著高于对照组，而插管后1min及切皮时收缩压、舒展压则显著低于对照组，P＜0.05。结论：针对行精神分类症手术治疗患者采用雷米芬太尼麻醉与芬太尼相比。可进一步稳定术中生命体征，控制应激反应，麻醉效果较好，值得推广应用。
|
| Abstract |
Objective: To compare the anesthetic effects of remifentanil and fentanyl in patients with schizophrenia. Methods: 100 patients with schizophrenia were treated surgically in our hospital from September 2015 to September 2018. According to the anesthesia scheme, 50 patients were divided into two groups. The control group was anesthetized with fentanyl and propofol during the operation, while the observation group was anesthetized with remifentanil and propofol. The changes of heart rate and blood pressure at different time points of anesthesia were recorded and compared between the two groups. Results: There was no significant difference in heart rate between the two groups before and 1 minute after anesthesia (P < 0.05); heart rate fluctuated in the observation group at different stages after anesthesia, in which 1 minute after intubation and skin incision were significantly lower than those in the control group, while at the end of operation and eye opening were significantly higher than those in the control group (P < 0.05); there was no statistical difference in systolic and diastolic blood pressure between the two groups before anesthesia, at the end of operation and The systolic and diastolic blood pressures in the observation group were significantly higher than those in the control group at 1 minute after anesthesia, while the systolic and diastolic blood pressures at 1 minute after intubation and skin incision were significantly lower than those in the control group (P < 0.05). CONCLUSION: Remifentanil anesthesia is better than fentanyl anesthesia for patients undergoing psychiatric surgery. It can further stabilize the vital signs, control the stress reaction and has a good anesthetic effect. It is worth popularizing and applying.
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| 关键词 |
雷米芬太尼；芬太尼；精神分裂症；生命体征
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| KeyWord |
remifentanil; fentanyl; schizophrenia; vital signs
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| 基金项目 |
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| 页码 |
107-109 |
李新帅*.
全身麻醉、椎管内麻醉应用于骨科手术患者(高龄)对其术后精神状态、认知功能的影响分析 [J].
国际精神病学杂志.
2020; 47; (1).
107 - 109.