Journal of International Psychiatry

Objective To explore correlation among poststroke depression with the neurological function recovery and the risk of stroke recurrence. Methods: The clinical data of stroke patients who were treated in our department from March 2017 to March 2018 and completed 1 year follow-up were retrospectively analyzed. 108 patients with acute phase depression (PSD) with stroke were selected as PSD group, and the same treatment was selected. The absence of PSD in 112 patients as a non-PSD group, analysis of the correlation between PSD and long-term functional recovery and risk of recurrence within 1 year. RESULTS: The NIHSS score, the stroke recurrence rate, and the mRS score in patients with moderate and severe PSD were higher than those in the patients without PSD and with light PSD (P<0.05)，Pearson regression model showed that there is a positive correlation between SDS score and NIHSS score（r=0.628，P<0.001）; multivariate logistic regression analysis showed that systolic blood pressure, PSD, NIHSS score 2 weeks after stroke, and 2 weeks post-stroke mRS score were risk factors for stroke recurrence within 1 year. Conclusions: PSD is significantly associated with long-term functional recovery and risk of recurrent stroke within 1 year. PSD patients have poor long-term functional recovery, and early detection and intervention of PSD may be helpful to improve stroke prognosis.

acute stroke depression; stroke recurrence; stroke