| Abstract |
Objective: To analyze the effects of supportive psychotherapy combined with escitalopram on circulatory alternating pattern (CAP) and social function in patients with depression. Methods: From June 2015 to July 2018, 118 patients with depression admitted to our hospital were selected and grouped into 59 cases each according to the treatment plan. The control group was treated with escitalopram, while the observation group was treated with supportive psychotherapy combined with escitalopram. The excellent and good rates, Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD-17), Social Deficiency Screening Scale (SDSS), Brief Psychiatric Rating Scale (BPRS), Serum Brain-derived Neurotrophic Factor (BDNF), CAP Time, CAP rate, A1, A2, A3 subtypes of the two groups were compared. Results: The excellent and good rate of the observation group (88.14%) was higher than that of the control group (66.10%) (P<0.05); the scores of HAMA and HAMD-17 in the observation group were lower than that in the control group (P<0.05); the scores of SDSS and BPRS in the observation group were lower than that in the control group (P<0.05); the level of serum BDNF in the observation group was higher than that in the control group (P<0.05); the time of CAP, CAP rate, A1, A2, A3 in the observation group were lower than that in the control group after the intervention Group B (P < 0.05). Conclusion: Supportive psychotherapy combined with escitalopram in the treatment of depression can improve anxiety and depression, alleviate clinical symptoms, promote social function, improve neuronal pathological state, and correct cyclic alternating mode activities, which has a remarkable effect.
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