| Abstract |
objective To explore the relationship between postoperative fat depression in patients with blood lipids and traumatic brain injury, in order to reduce the incidence of postoperative depression in patients with traumatic brain injury. Method Eighty-four patients with craniocerebral injury who were treated in our hospital from August 2017 to January 2019 were selected as subjects. Patients were divided into two groups according to whether there was depression (SDS score ≥ 53), and there were no depression in the control group. A total of 46 cases were observed and combined with depression. A total of 38 cases were observed. Blood lipid levels (total cholesterol TC, high-density lipoprotein cholesterol HDL-C, low-density lipoprotein cholesterol level LDL-C, and triglyceride TG) were compared between the two groups. Multivariate Logisitic was used to analyze the risk factors of postoperative depression in patients with traumatic brain injury, and Pearsons method was used to analyze the correlation between blood lipid levels and depression levels. Result The TC level of the observation group was 5.51±0.32mmol/L, the HDL-C level was 0.83±0.15mmol/L, the LDL-C level was 3.95±0.29mmol/L, and the TG level was 2.26±0.36mmol/L. The TC level of the control group was 4.21±0.25mmol/L, the HDL-C level was 1.26±0.15mmol/L, the LDL-C level was 3.02±0.24mmol/L, and the TG level was 1.09±0.30mmol/L(P<0.05). Multivariate Logisitic regression analysis showed that high TC levels, low HDL-C levels, high LDL-C levels, and high TG levels were risk factors for postoperative depression in patients with traumatic brain injury. Pearson analysis showed that the correlation coefficients r of SDS scores with TC, HDL-C, LDL-C and TG were 0.402, -0.227, 0.389, and 0.513, respectively. Conclusion There is a certain correlation between the occurrence of postoperative depression and blood lipid levels in patients with traumatic brain injury. The increase of TC level, LDL-C and TG levels, and the decrease of HDL-C level suggest that patients have the risk of depression, which should be paid attention to in clinic.
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