酒精使用障碍共病精神障碍患者的脑损害CT影像学特征分析
Cerbral CT Characteristics of Alcohol Use Disorder Co-occurrence with Psychonosema
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2019, 46(6) |
| 作者 |
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| 作者单位 |
商丘市第四人民医院影像放射科 ;
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| 摘要 |
目的：分析酒精使用障碍共患精神障碍患者的脑损害CT影像学改变。方法：选取 2015年10月-2018年3月在我院就诊的精神障碍患者327例，年龄24-71岁，平均（49.23±18.35）岁。根据是否共病酒精使用障碍分为共病组（n=148）和非共病组（n=179），另选取同时期在我院行脑CT检查的健康体检患者200例作为对照组。观察并比较各脑区CT值、脑萎缩程度、部位、脑白质变性等情况。采用 SPSS 22.0进行统计学分析。计量资料组间比较采用单因素方差分析，两两比较采用L-SD法；计数资料组间比较采用χ2 检验或Fisher精确检验。P <0.05差异有统计学意义。结果：共病组、非共病组及对照组患者在年龄、性别、BMI方面无统计学差异（P>0.05）。与对照组相比，共病组额叶、顶叶、颞叶CT值显著低于对照组（P<0.05），额叶CT值低于非共病组（P<0.05），脑白质密度显著低于非共病组（P=0.027）和对照组（P=0.06）。共病组双侧脑室前角、第三脑室宽度、脑沟宽度显著宽于非共病组和对照组（P<0.05）。共病组发现脑CT异常显著高于非共病组（P=0.031）和对照组（P=0.002）。结论：CT是一种准确、快捷的检查方式，能够评价酒精使用障碍共患精神障碍患者脑组织损害。
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| Abstract |
Objective：To explore the cerbral CT characteristics of clcohol use disorder co-occurrence with psychonosema.Methods：Cerbral CT scan was carried out on 327 patients of psychonosema in our hospital from Oct.2015 to Mar.2018, age arrange from 24-71years old, average (49.23±18.35) years. According to the presence or absence of alcohol use disorder, the patients were divided into comorbidity group (n=148) and non-comorbidity group (n=179). Another 200 healthy physical examination patients who underwent brain CT examination in our hospital during the same period were selected as the control group.The CT value, atrophy degree, location and white matter degeneration of each brain region were observed and compared.SPSS 22.0 was used for statistical analysis.One-way analysis of variancewas used for comparison between data groups, and l-sd method was used for pairwise comparison.Comparison of two - square test and Fishers exact test was conducted.P <0.05 was statistically significant.Results：There were no significant differences in age, sex and BMI between comorbidity group, non-comorbidity group and control group (P>0.05).Compared with the control group, the CT values of the frontal lobe, parietal lobe and temporal lobe in the comorbid group were significantly lower than those in the control group (P<0.05), the CT values of the frontal lobe were significantly lower than those in the non-comorbid group (P<0.05), and the white matter density was significantly lower than those in the non-comorbid group (P=0.027) and the control group (P=0.06).The width of anterior horn, third ventricle and sulcus in comorbid group were significantly wider than those in non-comorbid group and control group (P<0.05).Abnormal CT findings in the comorbidity group were significantly higher than those in the non-comorbidity group (P=0.031) and the control group (P=0.002).Conclusion：CT is an accurate and rapid imaging examination method, which can evaluate the brain tissue damage in patients with alcohol use disorder co-occurrence with psychonosema.
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| 关键词 |
酒精使用障碍；精神障碍；CT；共病
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| KeyWord |
Alcohol use disorder :Psychonosema: CT :co-occurrence
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| 基金项目 |
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| 页码 |
991-993 |
丁薇*.
酒精使用障碍共病精神障碍患者的脑损害CT影像学特征分析 [J].
国际精神病学杂志.
2019; 46; (6).
991 - 993.