重复经颅磁刺激治疗儿童孤独症的效果观察

Effect of repeated transcranial magnetic stimulation on children with autism

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2020, 47(2)
作者
作者单位

南阳市中心医院 小儿康复科 ;

摘要
目的:探讨儿童孤独症应用重复经颅磁刺激技术治疗效果及预后恢复情况。方法:选取孤独症患儿80例,均为我院精神病科2017年2月至2019年2月收治,采用随机数字表抽取法分组,就单纯采取常规康复训练方案治疗(对照组,n=40)与联用重复经颅磁刺激技术治疗(观察组,n=40)血清性激素水平、行为量表(ABC)评分、发育商(DQ)评分、症状量表(CARS)评分及ABC各因子评分情况展开对比。结果:两组治疗前,经对患儿机体血清性激素P、E2、LH测定显示,各指标水平无明显差异(P>0.05),治疗后,观察组测验值明显下降,对照组未见明显变化,观察组各指标测验值水平明显低于对照组,差异具有统计学意义(P<0.05)。两组治疗前,ABC量表、DQ量表、CARS量表评分经测验无差异(P>0.05),治疗后ABC、CARS评分经评测均有降低,DQ均有升高,且观察组降低和升高程度较对照组更为显著,差异具有统计学意义(P<0.05)。两组治疗前,ABC量表各维度即生活自理、感觉、语言表达、躯体运动、社会交往评分经测验无差异(P>0.05),治疗后,各测验分值较治疗前均有下降,但观察组语言功能、躯体运动、社会交往下降程度较对照组更为显著,差异具有统计学意义(P<0.05)。结论:儿童孤独症患者采用重复经颅磁刺激技术展开治疗,可发挥有效的对性激素水平调节的作用,并可纠正孤独症异常行为,减轻临床症状,促进心理发育,特别在语言功能、躯体运动、社会交往改善方面,效果更为突出,有非常重要的应用前景。
Abstract
Objective: To investigate the therapeutic effect and prognosis of children with autism using repeated transcranial magnetic stimulation. Methods: Eighty children with autism were selected. All of them were admitted to the Department of Psychiatry from February 2017 to February 2019. They were randomly divided into groups and were treated with routine rehabilitation training (control group, n=40). ) combined with transcranial magnetic stimulation (observation group, n=40) serum sex hormone level, behavioral scale (ABC) score, developmental quotient (DQ) score, symptom scale (CARS) score, and ABC factor score The situation is compared. RESULTS: Before the treatment, the serum levels of serum hormones P, E2 and LH in the two groups showed no significant difference in the levels of the indicators (P>0.05). After the treatment, the test values ​​of the observation group decreased significantly, and the control group showed no significant changes. The test value of each indicator in the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.05). Before treatment, the ABC scale, DQ scale and CARS scale scores were not different (P>0.05). After treatment, ABC and CARS scores were all evaluated, DQ increased, and the observation group decreased. The degree of elevation was more significant than that of the control group, and the difference was statistically significant (P<0.05). Before the treatment of the two groups, there was no difference in the dimensions of self-care, sensory, linguistic expression, physical exercise, and social interaction scores in the ABC scales (P>0.05). After treatment, the scores of each test decreased compared with before treatment, but The degree of decline in language function, physical activity, and social interaction in the observation group was more significant than that in the control group, and the difference was statistically significant (P<0.05). Conclusion: Children with autism can be treated with repeated transcranial magnetic stimulation to exert effective regulation of sex hormone levels, and can correct abnormal behaviors of autism, alleviate clinical symptoms and promote psychological development, especially in language function and body movement. In terms of improving social interaction, the effect is more prominent and has very important application prospects.
关键词
儿童;孤独症;重复经颅磁刺激技术;血清性激素水平、行为;发育商;症状
KeyWord
children; autism; repetitive transcranial magnetic stimulation; serum sex hormone levels, behavior; developmental quotient; symptoms
基金项目
页码 322-324
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任莉*. 重复经颅磁刺激治疗儿童孤独症的效果观察 [J]. 国际精神病学杂志. 2020; 47; (2). 322 - 324.

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