| Abstract |
Objective: To analyze the correlation between serum vitamin D level and depression in patients with polycystic ovary syndrome. Methods: 60 cases of patients with polycystic ovary syndrome in our hospital from May 2018 to May 2019 were randomly divided into two groups: one group with depression (combined group, 30 cases) and the other group without depression (non-combined group, 30 cases). The general data, DBP, SBP, FPG, 2hPG, FINS, HOMA-IR and TG, HDL-C, incidences of MS, serum [25 (OH) D] levels, BDI scores of the two groups were statistically analyzed. The risk factors of depression of patients with polycystic ovary syndrome were analyzed by multivariate logistic regression. Results: The body mass index (BMI) of the combined group was significantly higher (P < 0.05), the proportion of family history of depression was significantly higher (P < 0.05), the SBP, FINS were significantly higher (P < 0.05), the TG was significantly higher (P < 0.05), the incidence of MS 56.7% (17/30) was significantly higher than the non-combined group 33.3% (10/30) (P < 0.05), the serum [25 (OH) D] level was significantly lower (P < 0.05), the BDI score was significantly higher than thenon-combined group (P < 0.05). The serum [25 (OH) D] level was negatively correlated with BDI score (r=-0.361, P < 0.05). Multivariate logistic regression analysis showed that the risk factors of depression of patients with polycystic ovary syndrome included family history of depression, MS and serum [25 (OH) D] level < 11.5 ug/L (P < 0.05). Conclusion: Serum vitamin D level is closely related to depression of patients with polycystic ovary syndrome.
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