Journal of International Psychiatry

Objective: To study the clinical effect of fluoxetine in the treatment of elderly patients with epilepsy with mild to moderate depression. METHODS: Eighty-eight patients with senile epilepsy with mild to moderate depression who were treated in our hospital from August 2016 to December 2018 were enrolled in the study. They were randomly divided into two groups, the observation group and the control group, 44 cases each. . The control group received routine psychological counseling measures. The observation group was treated with fluoxetine on the basis of the control group. The total effective rate, SAS, SDS score, quality of life score, and sleep quality score were compared between the two groups. RESULTS: The sleep quality scores of the observation group were better than those of the control group at 2 weeks, 1 month, and 3 months. The effective rate of the observation group was 93.18% higher than that of the control group. The SAS and SDS scores before treatment were compared between the two groups. The difference was not statistically significant (P>0.05. After treatment, the SDS and SAS scores of the observation group were better than the control group; the quality of life scores of the observation group were better than the control group, P<0.05. Conclusion: The treatment of senile epilepsy with mild to moderate depression in patients with mild to moderate depression can effectively improve the quality of sleep and reduce depressive symptoms in patients with epilepsy, which can help improve the quality of life of patients, and the curative effect is significant. Learn from.

fluoxetine; senile epilepsy; mild to moderate depression; clinical effect