| Abstract |
Objective: To explore the clinical effect of Shugan Jieyu Decoction combined with Deanxit in the treatment of depression after cerebral infarction. Methods: 90 patients with cerebral infarction complicated with depression were studied. The study was conducted from July 2018 to July 2019. With the method of digital random table, the subjects of the study were divided into two groups and the control study was conducted, including the routine group and the research group, each of which accounted for 45 cases. The routine group was treated with Deanxit alone, while the research group was treated with Shugan Jieyu Decoction at the same time. The overall clinical efficacy, HAMDA depression score, SDS depression score, medication treatment time, mental state recovery time and adverse reactions were compared between the two groups. Result: The clinical curative effect of the study group was significantly higher than that of the routine group (p < 0.05). Before treatment, there was no significant difference in HAMD depression score and SDS depression score between the study group and the routine group (p < 0.05). After treatment for 1 week, 2 weeks, 3 weeks and 4 weeks, the HAMD depression score and SDS depression score of the study group were obvious. The scores of HAMD depression and SDS depression after treatment were lower than those before treatment (p < 0.05). The treatment time and mental state recovery time of the study group were significantly shorter than those of the routine group (p < 0.05). Compared with the routine group, the total adverse reactions of the study group were significantly shorter (p < 0.05). The incidence was significantly lower, and there was a significant difference between the two groups (p < 0.05). CONCLUSION: Compared with Deanxit alone, Shugan Jieyu Decoction can achieve higher clinical efficacy in patients with depression after cerebral infarction. It can also significantly reduce the degree of depression, shorten the time of medication treatment, and promote the early recovery of patientsmental state. The most important thing is that the combined medication scheme is not effective. With less adverse reactions and higher safety, it deserves to be highly valued and widely popularized in clinic.
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