| 摘要 |
探讨不同年龄段起病双相障碍患者临床特征的差异性。方法 选取双相障碍患者775例，按起病年龄将患者分为早发组（＜18岁）和成年组（≥18岁），通过自制的患者信息调查表采集患者的社会人口学和临床资料信息，对两组患者的上述信息进行对比分析。结果 与成年组双相障碍患者相比，早发组双相障碍患者具有以下特点：以男性居多[195(59.45)vs.231(51.68),x2=4.62,P=0.03]、自杀观念/行为发生率高[141(42.99)vs.151(33.78),x2=6.83,P=0.01]、5年内门诊复诊次数多[14.00(7.00,26.75)vs.11.00(5.00,22.00),Z=-3.50,P=0.00]、5年内再住院次数多[2.00(1.00,3.00)vs.1.00(1.00,3.00),Z=-3.46,P=0.00]。结论 起病年龄早的双相障碍患者以男性居多，自杀观念/行为发生率高，治疗依从性相对较好但疾病复发率高，提示预后差。
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| Abstract |
Objective To explore the differences in clinical characteristics of patients with bipolar disorder at different ages.Methods a total of 775 patients with bipolar disorder were selected and divided into early onset group (< 18 years old) and adult group (≥18 years old) according to the age of onset.Results Compared with adults with bipolar disorder, early onset bipolar disorder patients had the following characteristics:In the majority with men [195 (59.45) vs. 231 (51.68), x2 = 4.62, P = 0.03), high incidence of suicidal thoughts/behavior [141 (42.99) vs. 151 (33.78), x2 = 6.83, P = 0.01), the number of outpatient visits within five years after enrollment was higher[14.00 (7.00, 26.75) vs. 11.00 (5.00, 22.00), Z = 3.50, P = 0.00)], the number of rehospitalization within five years after enrollment was higher[2.00 (1.00, 3.00) vs. 1.00 (1.00,3.00), Z = 3.46, P = 0.00)]..Conclusion Male patients with bipolar disorder with early onset age are the majority, with high incidence of suicidal thoughts/behaviors, relatively good treatment compliance, but high recurrence rate of disease, suggesting poor prognosis.
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