颅脑外伤患者早期认知功能障碍危险因素调查

Risk Factors of Cognitive dysfunction in Patients with Traumatic Brain Injury

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DOI
刊名
Journal of International Psychiatry
年,卷(期) 2020, 47(3)
作者
作者单位

河南省濮阳市安阳地区医院神经外科 ;

摘要
研究颅脑外伤患者认知功能障碍的危险因素。方法 选择2016年4月-2019年4月我院收治的176例颅脑外伤患者,回顾性分析其病历资料,将并发认知功能障碍设为观察组,未出现认知功能障碍者设为对照组,比较两组相关临床资料,采用多因素Logistic回归分析颅脑外伤患者早期认知功能障的危险因素。结果 176例颅脑外伤患者出现早期认知功能障25例,发生率14.20%;观察组与对照组年龄、开放性创伤、受伤部位、入院美国国立卫生院卒中量表(NIHSS)评分、合并高血压、入院格拉斯哥昏迷评分(GCS)评分差异具有统计学意义(P<0.05);两组性别、受伤至治疗时间、合并糖尿病差异无统计学意义(P>0.05);多因素Logistic回归分析显示,年龄>60岁(OR=2.423)、开放性创伤(OR=3.156)、额叶受伤(OR=4.012)、颞叶受伤(OR=2.319)是颅脑外伤患者早期认知功能障的独立危险因素。结论 颅脑外伤患者容易发生认知功能障碍,受到年龄、开放性创伤、受伤部位等因素的影响,入院后应重视上述危险因素,采取针对性措施降低早期认知功能障风险。
Abstract
Objective To study the risk factors of cognitive dysfunction in patients with traumatic brain injury. Methods A total of 176 patients with traumatic brain injury treated in our hospital from April 2016 to April 2019 were selected, and their medical records were retrospectively analyzed. The concurrent cognitive dysfunction were set as the observation group, and those without cognitive dysfunction were set as the control group. The risk factors for cognitive dysfunction in patients with traumatic brain injury were analyzed using multivariate logistic regression. Results Twenty-five cases of cognitive dysfunction occurred in 176 patients with craniocerebral trauma, the incidence was 14.20%. The observation group and the control group had differences in age, open trauma, injury site, admission to the National Institutes of Health Stroke Scale (NIHSS) score, combined hypertension, and admission Glasgow Coma Scale (GCS) score with significant differences (P<0.05). There was no significant difference in gender, time from injury to treatment, and combined diabetes in the two groups (P>0.05). Multivariate Logistic regression analysis showed that age> 60 years (OR = 2.423), open trauma (OR = 3.156), frontal lobe injury (OR = 4.012), Temporal lobe injury (OR =2.319)were independent risk factors for cognitive dysfunction in patients with traumatic brain injury. Conclusion Patients with craniocerebral trauma are prone to cognitive dysfunction, which is affected by age, open trauma, injury site and other factors. After admission, the above-mentioned risk factors should be taken seriously and targeted measures should be taken to reduce cognitive dysfunction risk
关键词
颅脑外伤;认知功能障碍;危险因素
KeyWord
Traumatic Brain Injury; Cognitive dysfunction; Risk Factors
基金项目
页码 547-549
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李鹏强*. 颅脑外伤患者早期认知功能障碍危险因素调查 [J]. 国际精神病学杂志. 2020; 47; (3). 547 - 549.

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