抗抑郁治疗脑卒中后抑郁症患者治疗效果和依从性的影响
The effect of antidepressant on the treatment effect and compliance of patients with post-stroke depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(3) |
| 作者 |
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| 作者单位 |
延安大学咸阳医院 ;
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| 摘要 |
目的：观察抗抑郁药物治疗脑卒中后抑郁症患者的效果及对患者依从性的影响。方法：选取2017年8月~2019年8月我院收治的60例脑卒中后抑郁症患者作为研究对象，其中30例行常规治疗作为对照组，30例行抗抑郁药物治疗作为观察组，比较两组患者治疗效果。结果：两组间HAMD、NIHSS评分比较，治疗前无差异，治疗后观察组明显降低，与对照组比较P<0.05，差异有统计学意义；血清因子水平对比两组患者治疗后均有改善，但从改善程度来看观察组更好，与对照组比较P<0.05，有统计学意义；患者治疗依从性比较观察组VS对照组为93.3%VS70.0%，差异有统计学意义（P<0.05）。结论：抗抑郁治疗脑卒中后抑郁症患者对患者抑郁情绪、神经功能缺损状态改善作用显著，能够提升患者治疗依从性，可予以推广。
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| Abstract |
Objective: To observe the effect and compliance of antidepressants in the treatment of post-stroke depression. Methods: 60 patients with post-stroke depression admitted to our hospital from August 2017 to August 2019 were selected as the subjects of study, 30 of them were treated with routine therapy as the control group, 30 of them were treated with antidepressants as the observation group, and the therapeutic effects of the two groups were compared. Results: there was no difference in HAMD and NIHSS scores between the two groups before and after treatment, but the difference was statistically significant in the observation group , compared with the control group (P < 0.05); the level of serum factors in the observation group improved after treatment, but the improvement was better in the observation group, compared with the control group (P < 0.05), with statistical significance; patients treatment compliance in the observation group vs control ，The difference was statistically significant (P < 0.05).Conclusion: Antidepressant treatment of post-stroke patients with depression has a significant effect on the improvement of depression and neurological deficit, which can improve the treatment compliance of patients and can be promoted.
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| 关键词 |
抑郁；脑卒中；抑郁症；HAMD评分；依从性
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| KeyWord |
depression; stroke; depression; HAMD score; compliance
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| 基金项目 |
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| 页码 |
533-535 |
田智斌*.
抗抑郁治疗脑卒中后抑郁症患者治疗效果和依从性的影响 [J].
国际精神病学杂志.
2020; 47; (3).
533 - 535.