经颅磁刺激治疗原发性失眠的疗效及对神经内分泌的影响
he effect of transcranial magnetic stimulation on primary insomnia and neuroendocrine
ES评分 0
| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(4) |
| 作者 |
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| 作者单位 |
镇江市精神卫生中心 ;
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| 摘要 |
摘要：目的：探究在原发性失眠的治疗中应用低频重复经颅刺激（rTMS）治疗的临床效果及对患者神经内分泌的影响。方法：选取2019年5月~2020年4月这段时间内于本院进行治疗的原发性失眠患者70例，采用入院随机抽取单双号原则将其分为单号组（n=35）和双号组（n=35），单号组采用交变磁场疗法，双号组采用低频重复经颅磁刺激疗法。结果：单号组的治疗有效率为74.3％（26/35），低于双号组的94.3％（33/35）（P＜0.05）；单号组PSQI评分为（15.21±1.68）分，高于双号组的（10.09±2.17）分（P＜0.05）；单号组患者PSG量表中入睡时间、觉醒时间、总睡眠时间及睡眠效率评分依次为（46.27±5.32）分、（157.14±29.16）分、（295.27±41.25）分、（69.42±7.39）分，双号组依次为（30.28±4.27）分、（81.47±22.31）分、（345.36±34.69）分、（81.35±5.47）分，双号组各指标水平均较优（P＜0.05）；单号组患者皮质醇、Glu及Gly水平依次为（169.57±15.31）nmol/L、（17.12±1.87）nmol/L及（2.21±0.25）nmol/L，双号组依次为（224.07±15.32）nmol/L、（13.47±1.56）nmol/L及（2.86±0.35）nmol/L，双号组各指标水平较佳（P＜0.05）。
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| Abstract |
Abstract: Objective: To explore the clinical effect of low frequency repetitive transcranial stimulation (rTMS) in the treatment of primary insomnia and its effect on neuroendocrine. Methods: 70 patients with primary insomnia who were treated in our hospital from May 2019 to April 2020 were randomly divided into single group (n = 35) and double group (n = 35) according to the principle of single and double number. The single group was treated with alternating magnetic field and the double group was treated with low frequency repetitive transcranial magnetic stimulation. Results: the effective rate of single group was 74.3% (26 / 35), which was lower than that of double group (94.3% (33 / 35) (P < 0.05); the PSQI score of single group was (15.21 ± 1.68), which was higher than that of double group (10.09 ± 2.17) (P < 0.05); the scores of sleep time, wake-up time, total sleep time and sleep efficiency of single group were (46.27 ± 5.32), (157.14 ± 29.16 points, (295.27 ± 41.25) points, (69.42 ± 7.39) points, double group was (30.28 ± 4.27), (81.47 ± 22.31), (345.36 ± 34.69) points and (81.35 ± 5.47) points in turn, and the levels of cortisol, Glu and Gly were (169.57 ± 15.31) nmol / L, (17.12 ± 1.87) nmol / L and (2.21 ± 0.25) NMO / L respectively 1 / L, the two groups were (224.07 ± 15.32) nmol / L, (13.47 ± 1.56) nmol / L and (2.86 ± 0.35) nmol / L respectively, and the two groups had better indexes (P < 0.05).
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| 基金项目 |
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| 页码 |
730-732 |
陶晟*.
经颅磁刺激治疗原发性失眠的疗效及对神经内分泌的影响 [J].
国际精神病学杂志.
2020; 47; (4).
730 - 732.