Journal of International Psychiatry

[Abstract] objective: to investigate the changes of Pittsburgh sleep quality index (PSQI) score and its relationship with cognitive impairment in patients with post-surgery pain and depression. Methods: from October 2016 to October 2019, 90 patients with postoperative pain and depression in general surgery department were selected (depression group). Meanwhile, 90 patients with previous history of sleep disorder in general surgery department during the perioperative period were selected (control group). The PSQI index scores and cognitive function scores of the two groups were compared, and the correlation between the cognitive function scores and PSQI and the degree of depression in the depression group was analyzed by multiple linear regression method. Results: there was no significant difference in sleep quality, sleep efficiency and hypnotic score between the depression group and the control group (P>0.05). The sleep time, sleep time, sleep disturbance, daytime function and total PSQI scores of the depression group were all higher than those of the control group (P<0.05). Immediate memory, visual span, delayed memory and RBANS in the depression group were all lower than those in the control group (P<0.05). The results of multiple linear regression model showed that HAMD score and PSQI score were negatively correlated with the total RBANS of patients (P<0.05), and age and years of education were positively correlated with the total RBANS of patients (P<0.05). Conclusion: the patients with sleep disorders with postoperative pain and depression were more serious than those with simple sleep disorders, and the interaction between sleep disorders and depression had some adverse effects on the cognitive function of the patients.

【keywords】 depression; Sleep disorders; Pittsburgh sleep quality index; Cognitive impairment