| Abstract |
Abstract Purpose：The clinical features, prognosis and changes of multiphase personality of OCD were followed up for 4 years. To analyze the relationship between different therapeutic effects, different subtypes of OCD and the change of polyphasic personality.Method：A total of 153 patients with obsessive-compulsive disorder who completed the baseline assessment of the required data, including 89 males (58.2%) and 64 females (41.8%). (1) A self-made questionnaire was used to collect the clinical characteristics, treatment process, prognosis and course of disease of OCD. （2）The changes of clinical symptoms (YBOCS, HAMA, HAMD,) of patients with OCD were analyzed by self before and after control; The changes of MMPI were analyzed before and after treatment.Result：(1) The original group was 153, and 117 patients were followed up. The follow-up rate was 76.47%. 96.7% maintain diagnosis of obsessive-compulsive disorder. (2) About 41.9% had good prognosis, 33.3% had general prognosis, and 24.8% had poor prognosis. The duration of disease was 39 (33.3%), the duration of attack was 16 (13.7%), and the duration of fluctuation was 62 (53.0%). （3）During follow-up the HAMA score (8.7±4.8), the HAMD score (12.0±6.6), and the Y-BOCS score (16.4±8.4) were significantly lower than those at the time of enrollment (p<0.01). (4) The coding mode of the two MMPI assessment profiles is 2-7-4 or 7-2-4. Before and after comparison, the K, Hy, Hs, and Pa factor scores were significantly decreased, and the Re factor scores were increased, with significant differences (p<0.05). Significant differences in MMPI and clinical scales by prognosis.[Conclusion] Obsessive-compulsive disorder usually presents a chronic fluctuating course or a continuous course, and the prognosis is not optimistic. The change of morbid personality disorder (MMPI) is significantly correlated with prognosis, which proves that the abnormality of psychological characteristics plays an important role in the pathogenesis of OCD. According to MMPI clustering analysis, a new classification method for OCD was proposed, which may provide a basis for treatment selection of OCD.
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