脑外伤术后脑脊液漏伴颅内感染及焦虑抑郁的临床治疗
Clinical treatment of cerebrospinal fluid leakage with intracranial infection, anxiety and depression after brain injury
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(5) |
| 作者 |
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| 作者单位 |
咸阳市中心医院 ;
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| 摘要 |
摘要：目的：观察脑外伤术后脑脊液漏伴颅内感染及焦虑抑郁的临床治疗效果。方法：选取2018年1月-2019年12月我院收治的60例脑外伤术后脑脊液漏伴颅内感染及焦虑抑郁患者纳入研究对象，分组采用随机数字表法，观察组与对照组均为30例，分别实施腰大池置管持续引流、稀释头孢曲松注射、高压氧治疗与传统反复腰穿、稀释头孢曲松注射治疗。比较两组患者治疗前后SAS、SDS评分改善情况、病情控制情况及患者预后。结果：患者SAS、SDS经过治疗有所改善，与治疗前比较P<0.05，两组间比较观察组低于对照组（P<0.05），差异有统计学意义；统计学分析两组患者感染控制时间、临床症状缓解时间及住院时间，结果显示观察组显著短于对照组（P<0.05），差异有统计学意义；观察组脑脊液治愈率、重残率及死亡率分别为96.7%、3.3%、0.0%，与对照组比较差异有统计学意义（P<0.05）。结论：脑外伤术后脑脊液漏伴颅内感染及焦虑抑郁患者行腰大池置管持续引流配合高压氧治疗，对患者焦虑、抑郁情绪及临床症状改善作用显著，可予以推广。
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| Abstract |
Abstract: Objective: To observe the clinical therapeutic effect of cerebrospinal fluid leakage with intracranial infection and anxiety depression after brain injury. Methods: from January 2018 to December 2019, 60 cases of cerebrospinal fluid leakage with intracranial infection and anxiety and depression after brain injury were selected into the study object. The patients in the observation group and the control group were randomly divided into 30 cases. The patients in the observation group and the control group were treated with continuous lumbar cistern drainage, diluted ceftriaxone injection, hyperbaric oxygen treatment and traditional repeated lumbar puncture and diluted ceftriaxone injection respectively .The improvement of SAS and SDS scores, disease control and prognosis of the two groups were compared before and after treatment. Results:SAS and SDS were improved after treatment, compared with that before treatment P < 0.05, and the difference between the two groups was statistically significant (P < 0.05);Statistical analysis of infection control time, clinical symptom relief time and hospitalization time showed that the observation group was significantly shorter than the control group (P < 0.05), the difference was statistically significant;The cure rate, severe disability rate and mortality rate of CSF in the observation group were 96.7%, 3.3% and 0.0%, respectively, which were significantly different from those in the control group (P < 0.05).Conclusion: the continuous drainage of lumbar cistern with hyperbaric oxygen can improve the anxiety, depression and clinical symptoms of patients with cerebrospinal fluid leakage, intracranial infection and anxiety depression, which can be popularized.
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| 基金项目 |
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| 页码 |
1042-1044 |
刘振锋*.
脑外伤术后脑脊液漏伴颅内感染及焦虑抑郁的临床治疗 [J].
国际精神病学杂志.
2020; 47; (5).
1042 - 1044.