血清不饱和脂肪酸、维生素D及雌激素水平与产后抑郁的关系
Relationship between Serum Unsaturated Fatty Acids, Vitamin D and Estrogen Levels and Postpartum Depression
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2020, 47(6) |
| 作者 |
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| 作者单位 |
洛阳市妇幼保健院 ;
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| 摘要 |
【摘要】探讨血清不饱和脂肪酸、维生素D及雌激素水平与产后抑郁的关系。方法 选择我院2018年2月-2016年2月200例产后抑郁患者以及200名非抑郁患者为研究对象，分别设为抑郁组与非抑郁组，比较两组血清不饱和脂肪酸、维生素D及雌激素水平，并分析其与抑郁情绪的相关性。结果 抑郁组产后抑郁量表（EP-DS）评分显著高于对照组，血清20碳五烯酸(EPA)、生四烯酸(AA)、22碳六烯酸(DHA)水平均显著低于非抑郁组，(P<0.05)；抑郁组血清孕酮(P)、雌二醇(E2)、维生素D水平均显著低于非抑郁组，(P<0.05)；血清EPA、AA、 DHA水平、P、E2、维生素D水平与EP-DS评分呈显著负相关（P<0.05）。结论 产后抑郁的发生与发展可能与血清不饱和脂肪酸、维生素D及雌激素水平有关，应重视孕产妇产后相关血清指标动态变化，调整饮食结构，积极预防产后抑郁。
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| Abstract |
[Abstract] Objective To explore the relationship between serum unsaturated fatty acids, vitamin D and estrogen levels and postpartum depression. Methods A total of 200 patients with postpartum depression and 200 non-depressive patients from February 2018 to February 2016 in our hospital were selected as the study subjects. They were set as the depressive group and the non-depressive group. The levels of serum unsaturated fatty acids, vitamin D and estrogen in the two groups were compared, and their correlation with depression were analyzed. Results The depression group edinburgh postpartum depression scale (EP-DS) score was significantly higher than the control group. Serum levels of 20-carbon pentaenoic acid (EPA), tetratetraenoic acid (AA), and 22-carbon hexaenoic acid (DHA) were significantly lower than those in the non-depressive group (P<0.05). The levels of serum progesterone (P), estradiol (E2), and vitamin D in the depression group were significantly lower than those in the non-depression group (P<0.05). Serum EPA, AA, DHA levels, P, E2, and vitamin D levels were significantly negatively correlated with EP-DS scores (P<0.05). Conclusion The occurrence and development of postpartum depression may be related to serum unsaturated fatty acids, vitamin D and estrogen levels. Attention should be paid to the dynamic changes of maternal postpartum related serum indicators, adjusting the diet structure, and actively preventing postpartum depression.
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| 关键词 |
关键词：不饱和脂肪酸、维生素D；雌激素；产后抑郁
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| KeyWord |
Key words Unsaturated Fatty Acids, Vitamin D; Estrogen; Postpartum Depression
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| 基金项目 |
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| 页码 |
1169-1170 |
柳清梅*.
血清不饱和脂肪酸、维生素D及雌激素水平与产后抑郁的关系 [J].
国际精神病学杂志.
2020; 47; (6).
1169 - 1170.