International Journal of Clinical Research

Objective To explore the clinical application value of 24-hour dynamic electrocardiogram in middle-aged and elderly patients with heart failure. Methods 35 middle-aged and elderly heart failure patients admitted to our hospital from November 2021 to November 2024 were selected as the research group, and 35 healthy persons undergoing physical examination during the same period were selected as the control group. Both groups underwent 24-hour dynamic electrocardiogram testing to compare TMR (temporal modulation rate), LVEF (left ventricular ejection fraction), NT-proBNP (amino-terminal precursor of brain natriuretic peptide), T wave alternans (TWA) and dynamic electrocardiogram. Relevant indicators include standard deviation of normal to normal intervals (SDNN), heart rate (HR), root mean square deviation (rMSSD) and standard deviation of normal to normal intervals (SDANN). Results The TMR and LVEF of patients in the study group were significantly lower than those in the control group (P<0.05), while NT-proBNP and TWA were significantly higher than those in the control group (P<0.05). Dynamic electrocardiogram data showed that the SDNN, rMSSD and SDANN of the study group were significantly lower than those of the control group (P<0.05), and the HR was significantly higher than that of the control group (P<0.05). Conclusion 24-hour dynamic electrocardiogram has important clinical value in evaluating cardiac function, electrical activity stability and autonomic nervous function in middle-aged and elderly patients with heart failure, and is worthy of promotion and application in clinical practice.

Dynamic electrocardiogram; Middle-aged and elderly patients; Heart failure; Clinical