International Journal of Clinical Research

Objective To analyze the inpatient guidance of patients with uremic pruritus with hemodialysis combined with blood perfusion therapy, and to provide suggestions for patients healthy life. Methods 80 patients with uremic pruritus admitted from January 2024 to December 2024 were selected, and the control group was treated with hemodialysis; the observation group used hemodialysis combined with hemoperfusion to compare the clinical nursing effect. Results The duration, severity and attack frequency of skin pruritus in the observation group were better than those of the control group, with the significant difference (P <0.05); moreover, the immune function index in the observation group improved better than the control group, and the difference was significant (P <0.05). Finally, the serum endotoxin and β 2-MG levels in the observation group were lower than those of the control group after treatment, and the contrasts were significantly different (P <0.05). Conclusion Combined measures can be adopted in the treatment of patients with uremic pruritus. On the basis of hemodialysis, combined with hemoperfusion scheme can better improve the immune ability of patients, relieve pruritus symptoms, and the intervention effect is accurate.

Hemodialysis; Hemoperfusion; Uremic skin pruritus; Immune function; Clinical effect