International Journal of Clinical Research

Objective To study the level of NT-proBNP and its clinical correlation in chronic heart failure patients with atrial fibrillation in high altitude area. Methods The inpatient records of 200 patients with chronic heart failure in plateau area were retrospectively studied, and the patients were divided into atrial fibrillation group and non-atrial fibrillation group. Results A total of 200 patients with chronic heart failure were included. It was found that there were statistical differences in NT-proBNP level, left atrial diameter, left ventricular end-diastolic diameter and left ventricular ejection fraction between AF group and non-AF group (p < 0.05). The level of NT-proBNP in patients with chronic heart failure was positively correlated with left atrial diameter (r=0.63 p < 0.05), negatively correlated with left ventricular end-diastolic diameter (r=-0.16 p < 0.05), and negatively correlated with left ventricular ejection fraction (r=-0.28 p < 0.05). Conclusion In the clinical evaluation of chronic heart failure, the level of NT-proBNP can reflect ventricular remodeling and cardiac function. When chronic heart failure patients with atrial fibrillation, the level of NT-proBNP will be further increased, so this index can be used as a reference for early prediction of chronic heart failure patients with atrial fibrillation in plateau areas.

Chronic cardiac failure; Atrial fibrillation; NT-proBNP