International Journal of Clinical Research

Objective To explore and analyze the clinical effect of alginate gel dressing in gynecological anti human papillomavirus (HPV) infection. Methods A total of 102 patients with anti human papillomavirus (HPV) infection in the hospital from January 2024 to December 2024 were selected as the study subjects. Combined with the patients date of birth, the 102 patients were randomly divided into a control group and an observation group using a random number table method. The control group was treated with routine treatment, and the observation group was treated with alginate gel dressing. The immune function, HPV transformation and quality of life of the two groups were compared. The comparison of CD3+, CD4+, CD8+indicators, HPV viral load, and SF-36 score between the two groups before treatment showed no statistical significance, P＞0.05. After treatment, the observation group had higher levels of CD3+and CD4+compared to the control group, and lower levels of CD8+compared to the control group, P＜0.05. The HPV viral load in the observation group was lower than that in the control group, and the HPV seroconversion rate was higher than that in the control group, P＜0.05. After treatment, the SF-36 score of the observation group was higher than that of the control group, P＜0.05. Conclusion The alginate gel dressing can significantly improve the immune function, HPV transformation and quality of life of patients, which is worth popularizing and applying.

Human papillomavirus infection; Alginate gel dressing; Immune function status; HPV transformation status; Quality of life