International Journal of Clinical Research

Objective To explore the correlation between unexplained preterm birth and intrauterine infection in preterm infants in order to improve the survival rate of preterm infants. Methods A retrospective analysis was conducted on 120 preterm infants admitted to our department of the Daqing Peoples Hospital from January 2021 to December 2022. Among them, 80 preterm infants born due to unexplained preterm birth were assigned to the observation group, and 40 preterm infants born due to non-infectious factors were assigned to the control group. The levels of interleukin, C-reactive protein, procalcitonin, and the percentage of neutrophils were compared. Results The levels of inflammatory substances in the observation group were significantly higher than those in the control group, suggesting intrauterine infection in the amniotic fluid of the observation group. The comparison was statistically significant (P < 0.05). Conclusion Unexplained preterm birth is positively correlated with intrauterine infection in preterm infants. Elevated levels of inflammatory markers can be observed. Clinically, attention should be paid to analyzing the perinatal factors of the mother to prevent and be vigilant against intrauterine infection in preterm infants and improve their survival rate.

Premature birth of unknown cause; Correlation of intrauterine infection in premature infants; Premature rupture of membranes; Fetus; Pregnant woman