International Journal of Clinical Research

Objective To evaluate the impact of two intervention methods on the quality of life of spouses of patients with Helicobacter pylori infection, using traditional Chinese medicine mouthwash combined with acupoint patch therapy and dietary intervention based on the prevention before treatment theory for tonifying the spleen and kidneys. Methods A total of 90 spouses of patients with Helicobacter pylori infection who were tested negative for Helicobacter pylori infection and met the inclusion criteria at the Department of General Internal Medicine, Jiangsu Provincial Hospital of Traditional Chinese Medicine, were randomly divided into three groups: a control group of 30 cases, a group receiving traditional Chinese medicine decoction mouthwash, and a group receiving traditional Chinese medicine decoction mouthwash combined with acupoint patch therapy, each consisting of 30 cases. The changes in urea C13 Helicobacter pylori detection indicators, Health Survey Questionnaire (SF-36) scores, and overall efficacy scores were observed after 3 months of intervention. Results Compared with the control group, the DOB values of the experimental group 1 and the experimental group 2 showed statistically significant differences before and 3 months after the intervention, indicating that the DOB values were lower than before the intervention. The SF-36 scores within the three groups showed statistically significant differences before and after the intervention (P<0.05). The treatment effectiveness and significant efficiency of the experimental group 2 were higher than those of the experimental group 1 and the control group, with statistically significant differences (P<0.05). Conclusion The combination of traditional Chinese medicine mouthwash with the prevention before illness theory, which involves acupoint patch application and dietary intervention based on individual constitution, has reduced the positive rate of Helicobacter pylori infection among family members (spouses) of patients. This approach has significantly improved the quality of life for the patients spouses, embodying the concept and method of prevention before illness in traditional Chinese medicine. It holds significant clinical importance and social benefits for guiding future home-based TCM characteristic nursing care.

Helicobacter pylori infection; Chinese Medicine gargling; Acupoint patching; Constitution identification