International Journal of Clinical Research

Objective This study explores the efficacy evaluation of calcitriol combined with sevelamer carbonate in the treatment of patients undergoing maintenance hemodialysis. Methods One hundred patients undergoing maintenance hemodialysis, admitted between January 2021 and December 2024, were selected and randomly divided into a control group (50 cases, treated with sevelamer carbonate) and an observation group (50 cases, treated with calcitriol combined with sevelamer carbonate). The clinical treatment effects of the two groups were compared. Results The renal function indicators in the observation group were lower than those in the control group (P<0.05), the inflammatory indicators were lower than those in the control group (P<0.05), and the biochemical indicators were superior to those in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). The clinical treatment efficacy in the observation group was higher than that in the control group (P<0.05). Conclusion Calcitriol combined with sevelamer carbonate treatment can effectively control patients inflammatory responses, improve their renal function, and has high safety and application value.

Maintenance hemodialysis; Calcitriol; Sevelamer carbonate; Clinical efficacy