| Abstract |
【Abstract】Objective To explore the effect of sertraline in adjuvant treatment of patients with ventricular arrhythmia and its influence on negative emotions. Methods From June 2017 to October 2019, 90 patients with ventricular arrhythmia were selected and grouped according to the random number table method. 45 patients in the control group were treated with amiodarone, and 45 patients in the observation group were treated with adjuvant sertraline. Two months later, the number of ventricular arrhythmia, heart rhythm variability indicators, anxiety and depression, sleep quality and adverse reactions were compared between the two groups .Results: After treatment, the number of ventricular arrhythmias, HAMA, HAMD, and PSQI scores in the observation group were lower than those in the control group. SDNN, SDANN, RMSSD, and PNN50 were all higher than those in the control group, with statistical significance (P<0.05). The incidence of adverse reactions in the observation group was 8.89% higher than that in the control group 6.67%, which was not statistically significant (P>0.05). Conclusion: Sertraline adjuvant treatment of patients with ventricular arrhythmia can reduce the frequency of ventricular arrhythmia, promote heart function recovery, improve anxiety and depression and negative emotions. The drug is safe.
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