International Medical Research Frontier

The association mechanism between inflammatory response and cardiovascular disease has become a core area of modern medical research. Studies have shown that inflammatory response is closely related to the occurrence and development of cardiovascular disease by promoting pathological processes such as atherosclerotic plaque formation, myocardial injury and ventricular remodeling. Inflammatory markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) can not only serve as independent predictors of disease risk, but also play a key role in the early diagnosis and prognosis evaluation of myocardial infarction and heart failure. In terms of treatment strategies, anti-inflammatory drugs such as IL-1β inhibitors (Canakinumab) and comprehensive management programs targeting inflammatory pathways have been verified through clinical trials to significantly reduce the risk of cardiovascular events. Future research will focus on the precise threshold definition of inflammatory markers, biomarker discovery driven by multi-omics technology, and the optimization of individualized anti-inflammatory treatment strategies.

Inflammatory response; Cardiovascular disease; Atherosclerosis; C-reactive protein (CRP); Interleukin-6 (IL-6)