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[Abstract] Objective To explore the influence of psychosocial factors on the prognosis of children with antiepileptic drugs. Methods Eighty-eight children with epilepsy who were treated in our hospital from January 2019 to January 2020 were selected as the research objects. They were all treated with monotherapy and met the withdrawal criteria after the condition was controlled. The follow-up period of at least 1 year is regarded as the good prognosis group, and the recurrence within 1 year is regarded as the poor prognosis group. Evaluation of the Self-Rating Scale for Depression in Children (DSRSC), Child Anxiety and Emotional Disorders Screening Form (SCARED), Shame Scale for Primary and Middle School Students, Children’s Sleep Habits Questionnaire (CSHQ), Parent’s Highest Education Level, Marital Status, Discrimination Experience And other social and psychological factors. The good prognosis group and the poor prognosis group were subjected to univariate analysis, and the items with statistically significant differences were subjected to multivariate logistic regression analysis. Results Among 88 children with epilepsy, 24 children had a poor prognosis within 1 year of withdrawal. The difference in anxiety, depression, stigma, and sleep disturbance between the good prognosis group and the poor prognosis group was statistically significant (P<0.05). There was no significant difference between the two groups of parents in the highest education, marital status, and discrimination experience (P>0.05). Multivariate logistic regression analysis showed that anxiety, depression, and sleep disturbance are the factors affecting the prognosis of children with antiepileptic drugs. Conclusion Social and psychological factors have a significant impact on the short-term prognosis of childrens anti-epileptic drugs, including anxiety, depression, sleep disorders, etc., and psychological intervention and health education should be strengthened to consolidate the clinical efficacy.
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