International Journal of Medicine and Data

Novel drug delivery systems are of great significance in improving the bioavailability of poorly soluble drugs. Many drugs have low bioavailability due to poor water solubility, and traditional administration methods often fail to achieve the expected therapeutic effects. In recent years, with the advancement of drug delivery technology, new delivery systems such as nanoparticles, liposomes, and solid dispersions have been widely applied in the research of poorly soluble drugs. These novel systems significantly enhance drug bioavailability by improving drug solubility, controlling release rates, and increasing the stability of drugs in the body. This paper reviews the current research progress of novel drug delivery systems, discusses their mechanisms for enhancing the bioavailability of poorly soluble drugs, and provides an outlook on future development directions.

Drug delivery systems; Poorly soluble drugs; Bioavailability; Nanoparticles; Liposomes