恩替卡韦治疗失代偿期乙肝肝硬化的疗效及对患者心理状态的影响分析
Efficacy of entecavir in the treatment of decompensated hepatitis B cirrhosis and its influence on psychological state of patients
ES评分 0
| DOI |
| 刊名 |
Journal of International Psychiatry
|
| 年，卷(期) |
2022, 49(3) |
| 作者 |
|
| 作者单位 |
新乡市传染病医院 ;
|
| 摘要 |
[摘要]目的：分析失代偿期乙肝肝硬化患者接受恩替卡韦（ETV）治疗的疗效及对患者心理状态的影响。方法：将2019年5月—2020年5月接诊且行阿德福韦酯（ADV）治疗的40例失代偿期乙肝肝硬化患者作为对照组，将同期接诊且行ETV治疗的40例失代偿期乙肝肝硬化患者作为观察组，对组间肝功能指标、肝纤维化指标、血清细胞因子、心理状态评分、临床疗效展开分析。结果：（1）治疗6个月后，观察组肝功能指标、肝纤维化指标、血清细胞因子、心理状态评分优于对照组，P<0.05；（2）观察组2例无效（5.00%），对照组10例无效（25.00%），P<0.05。结论：对失代偿期乙肝肝硬化患者进行ETV治疗，可以增强疗效，改善患者肝功能及肝纤维化，减轻炎症反应，改善心理状态，值得推广。
|
| Abstract |
[Abstract] Objective: to analyze the effect of entecavir (ETV) on the psychological status of patients with decompensated hepatitis B cirrhosis. Methods: 40 patients with decompensated hepatitis B cirrhosis treated with adefovir dipivoxil (ADV) from May 2019 to may 2020 were selected as the control group, and 40 patients with decompensated hepatitis B cirrhosis treated with ETV during the same period were selected as the observation group. Results: (1) after 6 months of treatment, the indexes of liver function, liver fibrosis, serum cytokines and psychological state in the observation group were better than those in the control group (P < 0.05)（ 2) 2 cases in the observation group were invalid (5.00%), 10 cases in the control group were invalid (25.00%), P < 0.05. Conclusion: ETV treatment for patients with decompensated hepatitis B cirrhosis can enhance curative effect, improve liver function and liver fibrosis, reduce inflammatory reaction and improve psychological state, which is worthy of promotion.
|
| 关键词 |
关键词：恩替卡韦；失代偿期；乙肝；肝硬化；疗效；心理状态
|
| KeyWord |
Key words: entecavir; Decompensated period; Hepatitis B; cirrhosis; Curative effect; mentality
|
| 基金项目 |
|
| 页码 |
526-529 |
冯振清*.
恩替卡韦治疗失代偿期乙肝肝硬化的疗效及对患者心理状态的影响分析 [J].
国际精神病学杂志.
2022; 49; (3).
526 - 529.