Amplitude-Based Training in Secondary Parkinsonism and Parkinson Plus Syndrome: A Case Series-Advances in Geriatric Medicine and Research-CSCIED科技核心评价数据库-手机版

Amplitude-Based Training in Secondary Parkinsonism and Parkinson Plus Syndrome: A Case Series

Amplitude-Based Training in Secondary Parkinsonism and Parkinson Plus Syndrome: A Case Series

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DOI	10.20900/agmr20250010
刊名	Advances in Geriatric Medicine and Research AGMR
年，卷(期)	2025, 7(2)
作者	Rosemary Babcock,Nicole Dawson*,Hannah Dawkins,Emily Morrell,Erica Rappleyea,Holly Rogers,Morris Beato,
作者单位	Physical Therapy, Select Physical Therapy, Kissimmee, FL 34744, USA ; Division of Physical Therapy, College of Health Professions and Sciences, University of Central Florida, 12805 Pegasus Drive, Orlando, FL 32816, USA ;
摘要	Background and Purpose: The global and individual impact of Parkinson plus syndromes and secondary parkinsonism requires more insight into the treatment and management of these conditions. Previous studies highlighted the benefits of amplitude-based training on persons with Parkinson disease. However, there is a lack of evidence on the effects of this intervention on persons with Parkinson plus syndromes and secondary parkinsonism. The purpose of this case series is to examine the impact of amplitude-based training exercises on the gait, functional strength, dynamic balance, and balance confidence of five individuals with Parkinson plus syndrome or secondary Parkinsonism. Case Description: Five individuals were included in this case series including 3 subjects with vascular dementia with parkinsonism and 2 patients with multiple system atrophy. Intervention: The individuals received amplitude-based training exercises four times a week for four weeks in an outpatient setting. Each session was 60 minutes in length and comprised seven standardized exercises focusing on movement amplitude. Training on four different activities of daily living, sit-to-stand transfer, and gait training were also included in every session. Outcomes: All the participants showed improvement in outcome measures for gait speed, functional lower extremity strength, dynamic balance, and balance confidence with several individuals exceeding the minimum detectable change. Discussion: These findings highlight the success of amplitude-based training exercises in improving activity limitations and participation restrictions in persons with Parkinson plus syndromes, in particular those with vascular dementia with parkinsonism and multiple systems atrophy.
Abstract	Background and Purpose: The global and individual impact of Parkinson plus syndromes and secondary parkinsonism requires more insight into the treatment and management of these conditions. Previous studies highlighted the benefits of amplitude-based training on persons with Parkinson disease. However, there is a lack of evidence on the effects of this intervention on persons with Parkinson plus syndromes and secondary parkinsonism. The purpose of this case series is to examine the impact of amplitude-based training exercises on the gait, functional strength, dynamic balance, and balance confidence of five individuals with Parkinson plus syndrome or secondary Parkinsonism. Case Description: Five individuals were included in this case series including 3 subjects with vascular dementia with parkinsonism and 2 patients with multiple system atrophy. Intervention: The individuals received amplitude-based training exercises four times a week for four weeks in an outpatient setting. Each session was 60 minutes in length and comprised seven standardized exercises focusing on movement amplitude. Training on four different activities of daily living, sit-to-stand transfer, and gait training were also included in every session. Outcomes: All the participants showed improvement in outcome measures for gait speed, functional lower extremity strength, dynamic balance, and balance confidence with several individuals exceeding the minimum detectable change. Discussion: These findings highlight the success of amplitude-based training exercises in improving activity limitations and participation restrictions in persons with Parkinson plus syndromes, in particular those with vascular dementia with parkinsonism and multiple systems atrophy.
关键词	parkinsonism; Parkinson plus syndrome; case series; amplitude-based training
KeyWord	parkinsonism; Parkinson plus syndrome; case series; amplitude-based training
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Rosemary Babcock,Nicole Dawson*,Hannah Dawkins,Emily Morrell,Erica Rappleyea,Holly Rogers,Morris Beato. Amplitude-Based Training in Secondary Parkinsonism and Parkinson Plus Syndrome: A Case Series [J]. Advances in Geriatric Medicine and Research. 2025; 7; (2). - .

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