T Regulatory Cells in the Visceral Adipose Tissues

T Regulatory Cells in the Visceral Adipose Tissues

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DOI 10.20900/immunometab20220002
刊名
IJ
年,卷(期) 2022, 4(1)
作者
作者单位

[Fooks, Allen N.;
DCruz, Louise M.] Univ Pittsburgh, Dept Immunol, Pittsburgh, PA 15213 USA

摘要
CD4(+) Foxp(3+) T regulatory cells (Tregs) residing in the visceral adipose tissues (VAT) have profound effects on local and systemic metabolism. Although many of the molecular characteristics of VAT resident Tregs have been identified, how these cells promote metabolic homeostasis is still unclear. Several new publications help to illuminate the molecular mechanisms that underpin VAT resident Treg function and will be discussed here.
Abstract
CD4(+) Foxp(3+) T regulatory cells (Tregs) residing in the visceral adipose tissues (VAT) have profound effects on local and systemic metabolism. Although many of the molecular characteristics of VAT resident Tregs have been identified, how these cells promote metabolic homeostasis is still unclear. Several new publications help to illuminate the molecular mechanisms that underpin VAT resident Treg function and will be discussed here.
关键词
Tregs; adipose tissue; metabolism; obesity
KeyWord
Tregs; adipose tissue; metabolism; obesity
基金项目
页码 1-6
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Fooks, Allen N.; DCruz, Louise M.. T Regulatory Cells in the Visceral Adipose Tissues [J]. Immunometabolism. 2022; 4; (1). 1 - 6.

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