右美托咪定联合地佐辛对早发型重度子痫前期剖宫产术后临床疗效及负面情绪的影响
Effect of dexmedetomidine combined with dizocine on clinical efficacy and negative emotion after cesarean section in early-onset severe preeclampsia
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2022, 49(1) |
| 作者 |
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| 作者单位 |
郑州大学第三附属医院术后监护室 ;
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| 摘要 |
【摘要】目的：探讨右美托咪定联合地佐辛对早发型重度子痫前期剖宫产术后临床疗效及负面情绪的影响。方法：择取该院于2017年2月至2020年2月间，接收的早发型重度子痫前期剖宫产术患者共计90例，通过随机数字表法均分为观察组及对照组，一组45例。对照组行常规静脉泵入，观察组行右美托咪定+地佐辛镇痛。比较两组镇痛有效率、心率及血压指标、住院时间及咳嗽消失时间、术后疼痛评分、负面情绪评分。结果：观察组麻醉穿刺导管拔出后6小时、12小时、1日镇痛有效率显著高于对照组，组间具有差异性（P<0.05）；观察组心率、收缩压、舒张压指标均低于对照组，差异有统计学意义（P<0.05）；观察组住院时间、咳嗽消失时间均短于对照组，差异均具有统计学意义（P<0.05）。观察组术后各个阶段视觉模拟评分法(Visual Analogue Scale/Score，VAS)评分及负面情绪评分均低于对照组，两组比较形成差异性（P<0.05）。观察组并发症发生率8例（17.78%）和对照组12例（26.67%）比较，差异无统计学意义（P>0.05）。结论：实施右美托咪定联合地佐辛镇痛，可降低血压指标，缓解疼痛，稳定情绪。
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| Abstract |
[Abstract] Objective: To investigate the effect of dexmedetomidine combined with dezocine on clinical efficacy and negative emotion after cesarean section in early-onset severe preeclampsia. Methods: a total of 90 patients with early-onset severe preeclampsia received cesarean section in our hospital from February 2017 to February 2020 were randomly divided into observation group and control group, with 45 cases in one group. The control group received routine intravenous pumping, and the observation group received dexmedetomidine + dizocine to relieve pain. The effective rate of analgesia, heart rate and blood pressure, hospital stay, disappearance time of cough, postoperative pain score and negative emotion score were compared between the two groups. Results: the effective rate of analgesia in the observation group was significantly higher than that in the control group at 6 hours, 12 hours and 1 day after the extraction of anesthesia puncture catheter (P<0.05); The indexes of heart rate, systolic blood pressure and diastolic blood pressure in the observation group were lower than those in the control group (P<0.05); The hospital stay and cough disappearance time in the observation group were shorter than those in the control group (P < 0.05). The visual analogue scale / score (VAS) score and negative emotion score in the observation group were lower than those in the control group at all stages after operation. There was significant difference between the two groups (P <0.05). There was no significant difference in the incidence of complications between 8 cases (17.78%) in the observation group and 12 cases (26.67%) in the control group (P>0.05). Conclusion: Dexmedetomidine combined with dizocine can reduce blood pressure, relieve pain and stabilize mood.
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| 关键词 |
【关键词】右美托咪定；地佐辛；早发型重度子痫前期；剖宫产术；治疗价值
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| KeyWord |
[Key words] dexmedetomidine; Dizocine; Early onset severe preeclampsia; Cesarean section; Therapeutic value
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| 基金项目 |
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| 页码 |
137-140 |
刘秋瑾*.
右美托咪定联合地佐辛对早发型重度子痫前期剖宫产术后临床疗效及负面情绪的影响 [J].
国际精神病学杂志.
2022; 49; (1).
137 - 140.