Journal of International Psychiatry

[Abstract] Objective: To explore and analyze the clinical effect of hyperbaric oxygen + levodopa + psychological intervention on patients with ACI (acute cerebral infarction) aphasia. Methods: 86 patients with ACI aphasia hospitalized in our hospital from September 2018 to September 2020 were selected as the research objects. The research objects were randomly divided into observation group and control group according to the random number table method. 43 patients in the control group were treated with levodopa, and 43 patients in the observation group were treated with hyperbaric oxygen + levodopa + psychological intervention, The clinical efficacy of the two groups and the scores of Western Aphasia Examination (WAB), daily life Communication Ability Scale (CADL), self rating Anxiety Scale (SAS), self rating Depression Scale (SDS), Herth Hope Scale (HHI) and World Health Organization Quality of life scale (WHOQOL-BREF) before and after treatment were observed and compared. Results: The total clinical effective rate of the observation group (95.35%) was higher than that of the control group (67.44%) (P<0.05). After treatment, the WAB score, CADL score, HHI score and WHOQOL-BREF score of the observation group were higher than those of the control group, and the SAS score and SDS score of the observation group were lower than those of the control group (P<0.05). Conclusion: hyperbaric oxygen + levodopa + psychological intervention can effectively improve the aphasia symptoms of patients with ACI aphasia, improve their communication and communication ability, improve their hope level, improve their quality of life, anxiety and depression. It has definite clinical effect and is worthy of clinical application.

[Key words] hyperbaric oxygen; l-dopa; Psychological intervention; Acute cerebral infarction; Aphasia; Clinical efficacy