二氯异氰尿酸钠、咪鲜胺及其代谢物在杨梅贮藏保鲜中的消解动态及安全评价-食品安全质量检测学报-CSCIED科技核心评价数据库-手机版

二氯异氰尿酸钠、咪鲜胺及其代谢物在杨梅贮藏保鲜中的消解动态及安全评价

Degradation dynamics and safety evaluation of sodium dichloroisocyanurate, prochloraz and its metabolites in Myrica rubra Sieb. & Zucc storage and preservation

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DOI	10.19812/j.cnki.jfsq11-5956/ts.20250317008
刊名	食品安全质量检测学报 Journal of Food Safety and Quality
年，卷(期)	2025, 16(12)
作者	高萨, 史冉冉, 滕玲, 王炜涛, 杜雨婷, 罗婷, 杨桂玲, 王新全, 丁伟, 王豆2,
作者单位	东北农业大学植物保护学院; 浙江省农业科学院农产品质量安全与营养研究所; 杭州市乡村振兴服务中心
摘要	目的评估二氯异氰尿酸钠(sodium dichloroisocyanurate, DCCNa)、咪鲜胺及其代谢物在杨梅中的残留消解动态及其膳食摄入风险。方法采用液相色谱-串联质谱法(liquid chromatography-tandem mass spectrometry, LC-MS/MS)对常温和冷藏贮藏条件下杨梅中DCCNa、咪鲜胺及其代谢物2,4,6-三氯苯酚的残留动态进行定量分析, 并评估其膳食摄入风险。结果 DCCNa、咪鲜胺浸果的浓度与残留量之间存在正相关, 即浸果浓度越高, 初始残留量越高。两种农药在杨梅中的消解动态均符合一级动力学方程, 其中DCCNa在常温与冷藏条件下的半衰期分别为0.5~0.9 d和0.8~1.1 d, 而咪鲜胺分别为1.1~1.3 d和1.5~2.1 d, 且咪鲜胺的代谢物2,4,6-三氯苯酚的含量在贮藏期间呈现增加趋势。膳食风险评估结果显示, 用质量浓度为15 mg/L、60 mg/L的DCCNa和45 mg/L、180 mg/L的咪鲜胺溶液分别浸泡杨梅保鲜, 最高残留水平下杨梅中两种农药的急性膳食摄入风险均在可接受的范围内; 市售杨梅中DCCNa和咪鲜胺的残留水平低于实验处理组最终残留量, 且急性膳食摄入风险值小于100%, 处于可控范围内。结论本研究通过阐明DCCNa、咪鲜胺及其代谢物在杨梅贮藏保鲜过程中的降解规律, 为杀菌保鲜剂的科学规范使用和质量安全监管提供理论依据。
Abstract	Objective To evaluate the residue dissipation dynamics and dietary intake risks of sodium dichloroisocyanurate (DCCNa), prochloraz and its metabolites in Myrica rubra Sieb. & Zucc. Methods The residue dynamics of DCCNa, prochloraz and its metabolite 2,4,6-trichlorophenol in Myrica rubra Sieb. & Zucc under room temperature and cold storage conditions were quantitatively analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS), dietary intake risks were further assessed. Results There was a positive correlation between the concentration and residual amount of DCCNa and prochloraz in fruit soaking, indicating that higher dipping concentrations resulted in greater initial residues. The dissipation dynamics of both pesticides in Myrica rubra Sieb. & Zucc followed the first-order kinetics. The half-lives of DCCNa were 0.5–0.9 days at room temperature and 0.8–1.1 days under refrigeration, while those of prochloraz were 1.1–1.3 days and 1.5–2.1 days respectively. Additionally, the content of 2,4,6-trichlorophenol, a metabolite of prochloraz, exhibited an increasing trend during storage. Dietary risk assessment demonstrated that when Myrica rubra Sieb. & Zucc were treated with DCCNa (15 mg/L and 60 mg/L) or prochloraz (45 mg/L and 180 mg/L) solutions for preservation respectively, the acute dietary exposure risks of both pesticides in at the highest residue levels remained within the acceptable limits. Moreover, acute dietary risk values of DCCNa and prochloraz in commercially available Myrica rubra Sieb. & Zucc were lower than those in the experimental treatment groups, with all acute dietary exposure risks below 100%, indicating controllable exposure levels. Conclusion This study clarifies the degradation patterns of sodium DCCNa, prochloraz and their metabolites during the storage and preservation process of Myrica rubra Sieb. & Zucc, providing a theoretical basis for the scientific and standardized use of fungicidal preservatives as well as quality and safety regulation.
关键词	二氯异氰尿酸钠; 咪鲜胺; 2,4,6-三氯苯酚; 杨梅; 贮藏; 保鲜; 消解动态; 膳食风险评估
KeyWord	sodium dichloroisocyanurate; prochloraz; 2,4,6-trichlorophenol; Myrica rubra Sieb. & Zucc; storage; preservation; degradation dynamics; dietary risk assessment
基金项目
页码	97-105

参考文献
相关文献

[1]俞建忠, 陈列忠, 侯佳音, 等. 吡唑醚菌酯在杨梅和土壤中的残留及消解动态
[J]. 农药学学报, 2020, 22(5): 857–863. YU JZ, CHEN LZ, HOU JY, et al. Residue and dissipation dynamics of pyraclostrobin in waxberry (Myrica rubra) and soil
[J]. Chinese Journal of Pesticide Science, 2020, 22(5): 857–863.
[2]杨桂玲, 陆剑飞, 寿林飞, 等. 浙江省杨梅质量安全现状与风险隐患及对策
[J]. 农产品质量与安全, 2013(1): 20–22. YANG GL, LU JF, SHOU LF, et al. Current status, risk hazards and countermeasures of bayberry quality and safety in Zhejiang Province
[J]. Agricultural Product Quality and Safety, 2013(1): 20–22.
[3]YANG Z. Effect of high oxygen atmosphere storage on quality, antioxidant enzymes, and DPPH-radical scavenging activity of chinese bayberry fruit
[J]. Journal of Agricultural & Food Chemistry, 2009, 57(1): 176–81.
[4]王威, 严丽, 谢倩, 等. 预冷前后1-MCP处理对杨梅采后贮藏品质的影响
[J]. 热带作物学报, 2019, 40(7): 1406–1412. WANG W, YAN L, XIE Q, et al. Effects of pre-cooling timing and 1-MCP treatment on postharvest quality of Myrica rubra
[J]. Chinese Journal of Tropical Crops, 2019, 40(7): 1406–1412.
[5]ZHANG WS, CHEN KS, ZHANG B, et al. Postharvest responses of Chinese bayberry fruit
[J]. Postharvest Biology & Technology, 2005, 37(3): 241–251.
[6]ZHOU SH, FANG ZX, LV Y, et al. Phenolics and antioxidant properties of bayberry (Myrica rubra Sieb. et Zucc.) pomace
[J]. Food Chemistry, 2009, 112(2): 394–399.
[7]黄钰萍, 刘青娥. 1-MCP处理对杨梅果实贮藏期间品质及活性氧代谢的影响
[J]. 保鲜与加工, 2021, 21: 13–20. HUNG YP, LIU QE. Effects of 1-MCP treatment on qualities and reactive oxygen metabolism of Myrica rubra fruits during storage
[J]. Storage and Process, 2021, 21: 13–20.
[8]钱骅, 杨曙光, 陈斌, 等. 减压和1-MCP处理对杨梅保鲜效果的影响
[J]. 中国酿造, 2016, 35: 163–167. QIAN H, YANG SG, CHEN B, et al. Effect of hypobaric and 1-MCP treatments on fresh-keeping of Chinese bayberry
[J]. China Brewing, 2016, 35: 163–167.
[9]SU LY. Myrica rubra preharvest treatment with melatonin improves antioxidant and phenylpropanoid pathways during postharvest storage
[J]. Foods, 2025, 14(1): 64.
[10]程晓建, 王白坡, 喻卫武, 等. 杨梅果实贮藏保鲜技术研究
[J]. 江西农业大学学报, 2009, 31: 226–230. CHENG XJ, WANG BP, YU WW, et al. A study on the technology for storing and preserving Myrica rubra fruit
[J]. Acta Agriculthurae Universitatis Jiangxiensis, 2009, 31: 226–230.
[11]KIM YH, AN YJ, JO S, et al. Study on the test of the inhalation exposure of sodium dichloroisocyanurate (NaDCC) aerosols for the inhalation toxicity testing
[J]. Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research, 2019(314): 314.
[12]XIN J, MENG Z, QIAO Y, et al. Molecularly imprinted 2D photonic crystal hydrogel sensor for sodium dichloroisocyanurate
[J]. Analytical Methods: Advancing Methods and Applications, 2024(16): 7366–7371.
[13]戴振宇, 李川, 姜树林, 等. 二氯异氰尿酸钠的消毒特性及在养殖业中的应用
[J]. 江西畜牧兽医杂志, 2024(6): 29–31. DAI ZY, LI C, JIANG SL, et al. Disinfection characteristics of sodium dichloroisocyanurate and its application in the breeding industry
[J]. Jiangxi Animal Husbandry and Veterinary Journal, 2024(6): 29–31.
[14]陈平, 柳训才. 咪鲜胺的应用概况及其残留检测研究
[J]. 湖北农业科学, 2007, 46: 3. CHEN P, LIU XC. Overview of the application of prochloraz and research on its residue detection
[J]. Hubei Agricultural Sciences, 2007, 46: 3.
[15]HAO W, ZHONG G, HU M, et al. Control of citrus postharvest green and blue mold and sour rot by tea saponin combined with imazalil and prochloraz
[J]. Postharvest Biology & Technology, 2010, 56(1): 39–43.
[16]王妙, 陈武瑛, 熊浩, 等. 咪鲜胺及其代谢物三氯苯酚在百合植株中的残留检测方法及其动态研究
[J]. 植物医学, 2024, 3: 56–62. WANG M, CHEN WY, XIONG H, et al. Residue determination and dynamic research of prochloraz and its metabolite 2,4,6-truchlorophenol in lily plants
[J]. Plant Health and Medicine, 2024, 3: 56–62.
[17]李萍, 徐蓓蓓, 郑钦月, 等. 气相色谱-负化学源质谱法测定辣椒中咪鲜胺及2,4,6-三氯苯酚
[J]. 保鲜与加工, 2022, 22(9): 77–81. LI P, XU BB, ZHENG QY, et al. Detection of prochloraz and 2,4,6-trichlorophenol pesticide residues in pepper by GC-NCI MS/MS
[J]. Storage and Process, 2022, 22(9): 77–81.
[18]胡文彬, 魏琴芳, 叶琼环, 等. 气相色谱-串联质谱法测定葱中咪鲜胺及其代谢物2,4,6-三氯苯酚的含量
[J]. 实验室检测, 2023, 1(8): 20–25. HU WB, WEI QF, YE QH, et al. Determination of imidamine and its metabolite 2,4,6-trichlorophenol in greenonion by gas chromatography- tandem mass spectrometry
[J]. Laboratory Testing, 2023, 1(8): 20–25.
[19]冯馨, 张衡, 王传娅, 等. 负载型零价铁对水体中2,4,6-三氯苯酚的去除
[J]. 四川师范大学学报(自然科学版), 2018, 41(0): 654–661. FENG X, ZHANG H, WANG CY, et al. Removal of 2,4,6-trichlorophenol in water by supported zero-valent iron
[J]. Journal of Sichuan Normal University (Natural Science), 2018, 41(5): 654–661.
[20]SUN S, LIU Z, LI Q, et al. Molecular design of environment-friendly chlorophenol (CP) derivatives based on 3D-QSAR assisted with a comprehensive evaluation method combining bioaccumulation and degradation
[J]. Environmental Science and Pollution Research, 2023, 30: 83643–83656.
[21]浙江省市场监督管理局, 浙江省农业农村厅. 浙江省杨梅、桑葚食品安全专项治理方案
[Z]. 2022. Zhejiang Provincial Market Supervision Administration, Zhejiang Provincial Department of Agriculture and Rural Affairs. Special governance plan for food safety of waxberries and mulberries in Zhejiang Province
[Z]. 2022.
[22]ZHAO Y, KANG S, ZHOU LI, et al. Decay and residue dynamics of 25% prochlorazec in mandarin orange by simulating postharvest treatment at different storage temperatures
[J]. Journal of Food Processing & Preservation, 2013, 37(5): 496–502.
[23]FANG Q, YAO G, SHI Y, et al. Residue dynamics and risk assessment of prochloraz and its metabolite 2,4,6-trichlorophenol in apple
[J]. Molecules, 2017, 22(10): 1780.
[24]吴静娜, 韦璐阳, 邓有展, 等. 抑霉唑、咪鲜胺及其代谢物在荔枝贮藏保鲜中的残留动态及安全评价
[J]. 食品工业科技, 2024, 45(10): 234–241. WU JN, WEI LY, DENG YZ, et al. Residual dynamics and safety assessment of imazalil, prochloraz and their metabolites during fresh-keeping storage of litchi
[J]. Science and Technology of Food Industry, 2024, 45(10): 234–241.
[25]DENIS H, ARPáD A, ROLAND D, et al. Pesticide residues in food—acute dietary exposure
[J]. Pest Management Science, 2004, 60(4): 311–339.
[26]刘娜, 潘兴鲁, 张双, 等. 不同贮藏保鲜条件和加工过程对草莓及其加工产品中粉唑醇残留的影响
[J]. 食品工业科技, 2018, 39(14): 219–222. LIU N, PAN XL, ZHANG S, et al. Effect of storage and preservation and processingon the flutriafol residues in strawberry and processed products
[J]. Science and Technology of Food Industry, 2018, 39(14): 219–222.
[27]汪显群. 戊唑醇在梨果贮藏保鲜过程中的消解动态
[D]. 合肥: 安徽农业大学, 2018. WANG XQ. Dissipation dynamics of tebuconazole in pear during storage process
[D]. Hefei: Anhui Agricultural University, 2018.
[28]杜文瑜, 赵新玉, 韩鑫峰, 等. 异菌脲、咪鲜胺及其代谢物在哈密瓜贮藏保鲜中的降解动态及安全评价
[J]. 食品安全质量检测学报, 2024, 15(7): 62–67. DU WY, ZHAO XY, HAN XF, et al. Degradation dynamics and risk assessment of dietary exposure to iprodione, prochloraz and its metabolites during fresh-keeping storage of Hami cantaloupe
[J]. Journal of Food Safety & Quality, 2024, 15(7): 62–67.
[29]DANIELLE MP. Chlorinated isocyanurates: Dietary exposure scoping document
[Z]. 2018.
[30]Chemistry Book. Instructions for sodium dichloroisocyanurate (MSDS)
[EB/OL]. (2025-03-15)
[2017-08-11]. https://www.lookchem.cn/dictionary/ 16849.html
[31]赵慧宇, 刘银兰, 孙妍婕, 等. 杨梅中4种农药残留的膳食风险评估及家庭清洗去除效果
[J]. 农药学学报, 2021, 23(1): 146–153. ZHAO HY, LIU YL, SUN YJ, et al. Dietary risk assessment of 4 pesticides residue in bayberries and effect ofhoushold washing method on residue removal
[J]. Chinese Journal of Pesticide Science, 2021, 23(1): 146–153.

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高萨, 史冉冉, 滕玲, 王炜涛, 杜雨婷, 罗婷, 杨桂玲, 王新全, 丁伟*, 王豆*. 二氯异氰尿酸钠、咪鲜胺及其代谢物在杨梅贮藏保鲜中的消解动态及安全评价 [J]. 食品安全质量检测学报. 2025; 16; (12). 97 - 105.

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