Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease-Advances in Geriatric Medicine and Research-CSCIED科技核心评价数据库-手机版

Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease

Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease

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DOI	10.20900/agmr20240003
刊名	Advances in Geriatric Medicine and Research AGMR
年，卷(期)	2024, 6(2)
作者	Ria Minawala,Adam S. Faye*,
作者单位	1 Department of Medicine, NYU School of Medicine, New York, NY 10016, USA; 2 Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, NYU School of Medicine, New York, NY 10016, USA
Abstract	Sarcopenia, defined as a loss of muscle mass and function, is a physiologic factor that has been implicated as a predictor of adverse postoperative outcomes in many older adult populations. However, data related to sarcopenia in older adults with inflammatory bowel disease (IBD) remain limited. Older adults with IBD are particularly vulnerable to adverse postoperative outcomes, in part, due to muscle depletion from systemic inflammation, malnutrition, and reduced physical activity. However, few patients undergo routine muscle evaluation as a part of preoperative assessment. Moreover, cut-off values for measures of sarcopenia in the literature are modeled after non-IBD populations. The lack of standardized measures and values for sarcopenia in the IBD patient population has led to heterogenous findings and a paucity of preoperative risk stratification tools. Therefore, we aim to explore the scope of sarcopenia as a preoperative risk stratification tool among older adults with IBD.
KeyWord	IBD; muscle; surgery; ulcerative colitis; Crohn’s disease
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1. Vieujean S, Caron B, Jairath V, Benetos A, Danese S, Louis E, Peyrin-Biroulet L. Is it time to include older adults in inflammatory bowel disease trials? A call for action. Lancet Healthy Longev. 2022 May;3(5):e356-66. doi: 10.1016/S2666-7568(22)00060-5 2. Gisbert JP, Chaparro M. Systematic review with meta-analysis: inflammatory bowel disease in the elderly. Aliment Pharmacol Ther. 2014;39(5):459–77. 3. Carter MJ, Lobo AJ, Travis SP; IBD Section, British Society of Gastroenterology. Guidelines for the management of inflammatory bowel disease in adults. Gut. 2004 Sep;53(Suppl 5):V1-16. doi: 10.1136/gut.2004.043372 4. Bollegala N, Jackson TD, Nguyen GC. Increased Postoperative Mortality and Complications Among Elderly Patients With Inflammatory Bowel Diseases: An Analysis of the National Surgical Quality Improvement Program Cohort. Clin Gastroenterol Hepatol. 2016;14(9):1274–81. 5. Fernandez C, Gajic Z, Esen E, Remzi F, Hudesman D, Adhikari S, et al. Preoperative Risk Factors for Adverse Events in Adults Undergoing Bowel Resection for Inflammatory Bowel Disease: 15-Year Assessment of the American College of Surgeons National Surgical Quality Improvement Program. Am J Gastroenterol. 2023;118(12):2230–41. 6. Singh S, Boland BS, Jess T, Moore AA. Management of inflammatory bowel diseases in older adults. Lancet Gastroenterol Hepatol. 2023;8(4):368–82. 7. Hossain M, Yu D, Bikdeli B, Yu S. Sarcopenia and Adverse Post-Surgical Outcomes in Geriatric Patients: A Scoping Review. J Frailty Aging. 2021;10(1):63–9. 8. Du Y, Karvellas CJ, Baracos V, Williams DC, Khadaroo RG; Acute Care and Emergency Surgery (ACES) Group. Sarcopenia is a predictor of outcomes in very elderly patients undergoing emergency surgery. Surgery. 2014;156(3):521–7. 9. Dhaliwal A, Quinlan JI, Overthrow K, Greig C, Lord JM, Armstrong MJ, et al. Sarcopenia in Inflammatory Bowel Disease: A Narrative Overview. Nutrients. 2021;13(2):656. 10. Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr. 1997;127(5 Suppl):990S–1. 11. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(4):601. 12. Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020;21(3):300–7.e2. 13. Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci. 2014;69(5):547–58. 14. Xiao J, Caan BJ, Cespedes Feliciano EM, Meyerhardt JA, Peng PD, Baracos VE, et al. Association of Low Muscle Mass and Low Muscle Radiodensity With Morbidity and Mortality for Colon Cancer Surgery. JAMA Surg. 2020;155(10):942–9. 15. Gold SL, Raman M, Sands BE, Ungaro R, Sabino J. Review article: Putting some muscle into sarcopenia-the pathogenesis, assessment and clinical impact of muscle loss in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2023;57(11):1216–30. 16. Rodge GA, Goenka U, Jajodia S, Agarwal R, Afzalpurkar S, Roy A, et al. Psoas Muscle Index: A Simple and Reliable Method of Sarcopenia Assessment on Computed Tomography Scan in Chronic Liver Disease and its Impact on Mortality. J Clin Exp Hepatol. 2023;13(2):196–202. 17. Stone L, Olson B, Mowery A, Krasnow S, Jiang A, Li R, et al. Association Between Sarcopenia and Mortality in Patients Undergoing Surgical Excision of Head and Neck Cancer. JAMA Otolaryngol Head Neck Surgery. 2019;145(7):647–54. 18. Baracos VE. Psoas as a sentinel muscle for sarcopenia: a flawed premise. J Cachexia Sarcopenia Muscle. 2017;8(4):527–8. 19. Rutten IJG, Ubachs J, Kruitwagen RFPM, Beets-Tan RGH, Olde Damink, SWM, Van Gorp T. Psoas muscle area is not representative of total skeletal muscle area in the assessment of sarcopenia in ovarian cancer. J Cachexia Sarcopenia Muscle. 2017;8(4):630–8. 20. Wang J, Zhuang Q, Tan S, Xu J, Zhang Y, Yan M, et al. Loss of body weight and skeletal muscle negatively affect postoperative outcomes after major abdominal surgery in geriatric patients with cancer. Nutrition. 2023;106:111907. 21. Alipour O, Lee V, Tejura TK, Wilson ML, Memel Z, Cho J, et al. The assessment of sarcopenia using psoas muscle thickness per height is not predictive of post-operative complications in IBD. Scand J Gastroenterol. 2021;56(10):1175–81. 22. Albano D, Messina C, Vitale J, Sconfienza LM. Imaging of sarcopenia: old evidence and new insights. Eur Radiol. 2020;30(4):2199–208. 23. Lortie J, Rush B, Osterbauer K, Colgan TJ, Tamada D, Garlapati S, et al. Myosteatosis as a Shared Biomarker for Sarcopenia and Cachexia Using MRI and Ultrasound. Frontiers Rehabil Sci. 2022;3:896114. 24. Srpcic M, Jordan T, Popuri K, Sok M. Sarcopenia and myosteatosis at presentation adversely affect survival after esophagectomy for esophageal cancer. Radiol Oncol. 2020;54(2):237–46. 25. Quint EE, Liu Y, Shafaat O, Ghildayal N, Crosby H, Kamireddy A, et al. Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates. Am J Transplant. 2024 Apr;24(4):591-605. 26. Inose H, Yamada T, Hirai T, Yoshii T, Abe Y, Okawa A. The impact of sarcopenia on the results of lumbar spinal surgery. Osteoporos Sarcopenia. 2018;4(1):33–6. 27. Chianca V, Albano D, Messina C, Gitto S, Ruffo G, Guarino S, et al. Sarcopenia: imaging assessment and clinical application. Abdom Radiol 2022;47(9):3205–16. 28. Gonzalez MC, Heymsfield SB. Bioelectrical impedance analysis for diagnosing sarcopenia and cachexia: what are we really estimating? J Cachexia Sarcopenia Muscle. 2017;8(2):187–9. 29. Aleixo GFP, Shachar SS, Nyrop KA, Muss HB, Battaglini CL, Williams GR. Bioelectrical Impedance Analysis for the Assessment of Sarcopenia in Patients with Cancer: A Systematic Review. Oncologist. 2020;25(2):170–82. 30. Tamura T, Sakurai K, Nambara M, Miki Y, Toyokawa T, Kubo N, et al. Adverse Effects of Preoperative Sarcopenia on Postoperative Complications of Patients With Gastric Cancer. Anticancer Res. 2019;39(2):987–92. 31. Berger M, Yamada A, Komaki Y, Komaki F, Cohen RD, Dalal S, et al. Low Skeletal Muscle Index Adjusted for Body Mass Index Is an Independent Risk Factor for Inflammatory Bowel Disease Surgical Complications. Crohns Colitis 360. 2020;2(3):otaa064. 32. Faye AS, Kim M, Dane B, Delau O, Chodosh J, Adhikari S, et al. Skeletal Muscle is a Better Predictor of Postoperative Outcomes Among Older Adults with IBD as Compared to Psoas Muscle. Gastroenterology. 2023;164:6. 33. De A, Kumari S, Kaur A, Singh A, Kalra N, Singh V. Hand-grip strength as a screening tool for sarcopenia in males with decompensated cirrhosis. Indian J Gastroenterol. 2022;41(3):284–91. 34. Matsui R, Inaki N, Tsuji T, Momosaki R, Fukunaga T. Impact of Preoperative Handgrip Strength on Postoperative Outcome after Radical Gastrectomy for Gastric Cancer Patients. J Clin Med. 2022;11(23):7129. 35. Chang CM, Lee CH, Shih CM, Wang SP, Chiu YC, Hsu CE. Handgrip strength: a reliable predictor of postoperative early ambulation capacity for the elderly with hip fracture. BMC Musculoskelet Disord. 2021;22(1):103. 36. Hanada M, Yamauchi K, Miyazaki S, Oyama Y, Yanagita Y, Sato S, et al. Short-Physical Performance Battery (SPPB) score is associated with postoperative pulmonary complications in elderly patients undergoing lung resection surgery: A prospective multicenter cohort study. Chron Respir Dis. 2020;17:1479973120961846. 37. Asscher VER, Waars SN, van der Meulen-de Jong AE, Stuyt RJL, Baven-Pronk AMC, van der Marel S, et al. Deficits in Geriatric Assessment Associate With Disease Activity and Burden in Older Patients With Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2022;20(5):e1006-21. 38. Papadimitriou K, Detopoulou P, Soufleris K, Voulgaridou G, Tsoumana D, Ntopromireskou P, et al. Nutritional Risk and Sarcopenia Features in Patients with Crohn's Disease: Relation to Body Composition, Physical Performance, Nutritional Questionnaires and Biomarkers. Nutrients. 2023;15(16):3615. 39. Bahat G, Ozkok S, Kilic C, Karan MA. SARC-F Questionnaire Detects Frailty in Older Adults. J Nutr Health Aging. 2021;25(4):448-53. doi: 10.1007/s12603-020-1543-9 40. Ergenc I, Ismail Basa C, Uzum A, Sahin S, Kani HT, Aslan R, et al. High prevalence of muscle weakness and probable sarcopenia in patients with inflammatory bowel disease. Nutr Clin Pract. 2024. doi: 10.1002/ncp.11125 41. Nardone OM, de Sire R, Petito V, Testa A, Villani G, Scaldaferri F, et al. Inflammatory Bowel Diseases and Sarcopenia: The Role of Inflammation and Gut Microbiota in the Development of Muscle Failure. Front Immunol. 2021;12:694217. 42. Papadimitriou K. Effect of resistance exercise training on Crohn's disease patients. Intest Res. 2021 Jul;19(3):275-281. doi: 10.5217/ir.2020.00043 43. Bian AL, Hu HY, Rong YD, Wang J, Wang JX, Zhou XZ. A study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-α. Eur J Med Res. 2017;22(1):25. 44. Dalle S, Rossmeislova L, Koppo K. The Role of Inflammation in Age-Related Sarcopenia. Front Physiol. 2017;8:1045. 45. Pizzoferrato M, de Sire R, Ingravalle F, Mentella MC, Petito V, Martone AM, et al. Characterization of Sarcopenia in an IBD Population Attending an Italian Gastroenterology Tertiary Center. Nutrients. 2019;11(10):2281. 46. Adams DW, Gurwara S, Silver HJ, Horst SN, Beaulieu DB, Schwartz DA, et al. Sarcopenia Is Common in Overweight Patients with Inflammatory Bowel Disease and May Predict Need for Surgery. Inflamm Bowel Dis. 2017;23(7):1182–6. 47. Solem CA, Loftus EV Jr, Tremaine WJ, Harmsen WS, Zinsmeister AR, Sandborn WJ. Correlation of C-reactive protein with clinical, endoscopic, histologic, and radiographic activity in inflammatory bowel disease. Inflamm Bowel Dis. 2005 Aug;11(8):707-12. doi: 10.1097/01.mib.0000173271.18319.53 48. Ticinesi A, Nouvenne A, Cerundolo N, Catania P, Prati B, Tana C, et al. Gut Microbiota, Muscle Mass and Function in Aging: A Focus on Physical Frailty and Sarcopenia. Nutrients. 2019;11(7):1633. 49. Grosicki GJ, Fielding RA, Lustgarten MS. Gut Microbiota Contribute to Age-Related Changes in Skeletal Muscle Size, Composition, and Function: Biological Basis for a Gut-Muscle Axis. Calcif Tissue Int. 2018;102(4):433–42. 50. Chew W, Lim YP, Lim WS, Chambers ES, Frost G, Wong SH, et al. Gut-muscle crosstalk. A perspective on influence of microbes on muscle function. Front Med. 2023;9:1065365. 51. Khan I, Ullah N, Zha L, Bai Y, Khan A, Zhao T, et al. Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome. Pathogens. 2019;8(3):126. 52. Lu ZL, Wang TR, Qiao YQ, Zheng Q, Sun Y, Lu JT, et al. Handgrip Strength Index Predicts Nutritional Status as a Complement to Body Mass Index in Crohn's Disease. J Crohns Colitis. 2016;10(12):1395–400. 53. Dua A, Corson M, Sauk JS, Jaffe N, Limketkai BN. Impact of malnutrition and nutrition support in hospitalised patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2023;57(8):897–906. 54. Balestrieri P, Ribolsi M, Guarino MPL, Emerenziani S, Altomare A, Cicala M. Nutritional Aspects in Inflammatory Bowel Diseases. Nutrients. 2020;12(2):372. 55. Jabłońska B, Mrowiec S. Nutritional Status and Its Detection in Patients with Inflammatory Bowel Diseases. Nutrients. 2023;15(8):1991. 56. Zheng X, Zhu Y, Zhao Z, Chu Y, Yang W. The role of amino acid metabolism in inflammatory bowel disease and other inflammatory diseases. Front Immunol. 2023;14:1284133. 57. Nishikawa H, Nakamura S, Miyazaki T, Kakimoto K, Fukunishi S, Asai A, et al. Inflammatory Bowel Disease and Sarcopenia: Its Mechanism and Clinical Importance. J Clin Med. 2021;10(18):4214. 58. Fletcher J, Cooper SC, Ghosh S, Hewison M. The Role of Vitamin D in Inflammatory Bowel Disease: Mechanism to Management. Nutrients. 2019;11(5):1019. 59. Steffl M, Bohannon RW, Sontakova L, Tufano JJ, Shiells K, Holmerova I. Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis. Clin Interv Aging. 2017;12:835–45. 60. Uhlir V, Stallmach A, Grunert PC. Fatigue in patients with inflammatory bowel disease-strongly influenced by depression and not identifiable through laboratory testing: a cross-sectional survey study. BMC Gastroenterol. 2023;23(1):288. 61. Iida H, Seki T, Sakai Y, Watanabe T, Wakao N, Matsui H, et al. Low muscle mass affect hip fracture treatment outcomes in older individuals: a single-institution case-control study. BMC Musculoskelet Disord. 2021;22(1):259. 62. Lee EC, Park SJ, Lee SD, Han SS, Kim SH. Effects of Sarcopenia on Prognosis After Resection of Gallbladder Cancer. J Gastrointest Surg. 2020;24(5):1082–91. 63. Wang H, Yang R, Xu J, Fang K, Abdelrahim M, Chang L. Sarcopenia as a predictor of postoperative risk of complications, mortality and length of stay following gastrointestinal oncological surgery. Ann R Coll Surg Engl. 2021;103(9):630–7. 64. Pedersen M, Cromwell J, Nau P. Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2017;23(10), 1867-72. 65. Zhang T, Cao L, Cao T, Yang J, Gong J, Zhu W, et al. Prevalence of Sarcopenia and Its Impact on Postoperative Outcome in Patients With Crohn's Disease Undergoing Bowel Resection. JPEN J Parenter Enter Nutr. 2017;41(4):592–600. 66. Ryan E, McNicholas D, Creavin B, Kelly ME, Walsh T, Beddy D. Sarcopenia and Inflammatory Bowel Disease: A Systematic Review. Inflamm Bowel Dis. 2019;25(1):67–73. 67. Ge X, Xia J, Wu Y, Ye L, Liu W, Qi W, et al. Sarcopenia assessed by computed tomography is associated with colectomy in patients with acute severe ulcerative colitis. Eur J Clin Nutr. 2022;76(3):410–8. 68. Bamba S, Sasaki M, Takaoka A, Takahashi K, Imaeda H, Nishida A, et al. Sarcopenia is a predictive factor for intestinal resection in admitted patients with Crohn's disease. PLoS One. 2017;12(6):e0180036. 69. Kochar B, Orkaby AR, Ananthakrishnan AN, Ritchie CS. Frailty in inflammatory bowel diseases: an emerging concept. Therap Adv Gastroenterol. 2021 Sep 24;14:17562848211025474. 70. Keevil VL, Romero-Ortuno R. Ageing well: a review of sarcopenia and frailty. Proc Nutr Soc. 2015 Nov;74(4):337-47. doi: 10.1017/S0029665115002037 71. Wu J, Chi H, Kok S, Chua JMW, Huang XX, Zhang S, et al. Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery. Ann Coloproctol. 2023. doi: 10.3393/ac.2022.01207.0172 72. Gillis C, Buhler K, Bresee L, Carli F, Gramlich L, Culos-Reed N, et al. Effects of Nutritional Prehabilitation, With and Without Exercise, on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis. Gastroenterology. 2018;155(2):391–410.e4. 73. Molenaar CJL, Minnella EM, Coca-Martinez M, Ten Cate DWG, Regis M, Awasthi R, et al. Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial. JAMA Surg. 2023;158(6):572–81. 74. Cronin O, Barton W, Moran C, Sheehan D, Whiston R, Nugent H, et al. Moderate-intensity aerobic and resistance exercise is safe and favorably influences body composition in patients with quiescent Inflammatory Bowel Disease: a randomized controlled cross-over trial. BMC Gastroenterol. 2019;19(1):29. 75. Seeger WA, Thieringer J, Esters P, Allmendinger B, Stein J, Schulze H, et al. Moderate endurance and muscle training is beneficial and safe in patients with quiescent or mildly active Crohn's disease. United Eur Gastroenterol J. 2019;8(7):804–13. 76. Engels M, Cross RK, Long MD. Exercise in patients with inflammatory bowel diseases: current perspectives. Clin Exp Gastroenterol. 2017;11:1–11. 77. Fiorindi C, Cuffaro F, Piemonte G, Cricchio M, Addasi R, Dragoni G, et al. Effect of long-lasting nutritional prehabilitation on postoperative outcome in elective surgery for IBD. Clin Nutr. 2021;40(3):928–935. 78. Subramaniam K, Fallon K, Ruut T, Lane D, McKay R, Shadbolt B, et al. Infliximab reverses inflammatory muscle wasting (sarcopenia) in Crohn's disease. Aliment Pharmacol Ther. 2015;41(5):419–28. 79. Zhang T, Ding C, Xie T, Yang J, Dai X, Lv T, et al. Skeletal muscle depletion correlates with disease activity in ulcerative colitis and is reversed after colectomy. Clin Nutr. 2017;36(6):1586–92.

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Ria Minawala,Adam S. Faye*. Sarcopenia as a Preoperative Risk Stratification Tool among Older Adults with Inflammatory Bowel Disease, Advances in Geriatric Medicine and Research. 2024; 6; (2). https://doi.org/10.20900/agmr20240003.

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