Journal of International Psychiatry

[Abstract] Objective To explore the effects of dexzopiclone and sleep bundling mode on patients with hypertension and sleep disorders and their effects on mental resilience and sleep quality. Methods A total of 96 patients with hypertension and sleep disorders in our hospital from October 2020 to October 2022 were selected and divided into groups according to the lottery method. Both groups were given routine antihypertensive treatment, the control group was given sleep bundling mode intervention, and 48 cases in the observation group were treated with dexzopiclone. The blood pressure levels of the two groups were compared: diastolic blood pressure and systolic blood pressure. Sleep quality: Pittsburgh Sleep Quality Index (PSQI) score; Psychological resilience: Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD); Cognitive function: Brief Psychiatric Status Checklist (MMSE), Pathological Behavior Scale (BEHA VE-AD) and adverse reactions. Results: After treatment, there was no statistical significance in MMSE, BEHA VE-AD score, diastolic blood pressure, systolic blood pressure and incidence of adverse reactions in 2 groups (P>0.05). After treatment, the scores of PSQI, HAMA and HAMD in the observation group were lower than those in the control group, with statistical significance (P<0.05). Conclusion: Dexzopiclone combined with sleep clustering mode can effectively improve blood pressure and sleep quality, reduce negative emotions, improve cognitive function, and have high safety in the treatment of patients with hypertension and sleep disorders.

【 Key words 】 Dexzopiclone; Sleep clustering pattern; High blood pressure; Sleep disorders; Mental state