丙戊酸钠、拉莫三嗪联合心理干预对癫痫患儿认知功能、生活质量及心理状况的影响
The effect of sodium valproate and lamotrigine combined with psychological intervention on cognitive function, quality of life, and psychological status in children with epilepsy
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| DOI |
| 刊名 |
Journal of International Psychiatry
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| 年，卷(期) |
2023, 50(6) |
| 作者 |
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| 作者单位 |
徐州医科大学附属医院儿科 ;
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| 摘要 |
【摘要】目的：探讨在癫痫患儿治疗中，选择丙戊酸钠、拉莫三嗪联合心理干预的价值，并分析该方案对患儿认知功能、生活质量、心理状况的影响。方法：选取2020年1月~2022年12月范围内本院收治的100例癫痫患儿研究，以随机数字表法分2组处理，一组接受丙戊酸钠联合拉莫三嗪治疗（对照组），一组接受丙戊酸钠、拉莫三嗪联合心理干预治疗（观察组），分析2组临床疗效、认知功能、生活质量、癫痫发作次数、心理状况。结果：观察组50例患儿经丙戊酸钠联合拉莫三嗪治疗后，统计的临床疗效高于对照组（P<0.05）；观察组统计的认知功能评分高于对照组（P<0.05）；观察组生活质量评分高于对照组（P<0.05）；观察组癫痫发作次数低于对照组（P<0.05）；观察组。结论：丙戊酸钠、拉莫三嗪联合心理干预对在癫痫患儿治疗中可行性较高，通过改善其认知功能及心理状态，可减轻疾病对患儿生活质量的影响。
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| Abstract |
Abstract: Objective: To explore the value of choosing sodium valproate and lamotrigine combined with psychological intervention in the treatment of children with epilepsy, and to analyze the impact of this plan on cognitive function, quality of life, and psychological status of patients. Methods: A study was conducted on 100 children with epilepsy admitted to our hospital from January 2020 to December 2022. The study was divided into two groups using a random number table method. One group received sodium valproate combined with lamotrigine treatment (control group), and the other received sodium valproate and lamotrigine combined with psychological intervention treatment (observation group). The clinical efficacy, cognitive function, quality of life, seizure frequency, and psychological status of the two groups were analyzed. Results: After treatment with sodium valproate combined with lamotrigine, the clinical efficacy of 50 patients in the observation group was statistically higher than that in the control group (P<0.05); The cognitive function score of the observation group was higher than that of the control group (P<0.05); The quality of life score of the observation group was higher than that of the control group (P<0.05); The number of seizures in the observation group was lower than that in the control group (P<0.05); Observation group. Conclusion: The combination of sodium valproate and lamotrigine with psychological intervention is highly feasible in the treatment of epilepsy in children. By improving their cognitive function and psychological state, the impact of the disease on the quality of life of patients can be reduced.
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| 关键词 |
关键词：丙戊酸钠；拉莫三嗪；心理干预；癫痫；认知功能；生活质量；癫痫发作次数
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| KeyWord |
Keywords: sodium valproate; Lamotrigine; Psychological intervention; Epilepsy; Cognitive function; Quality of life; Number of seizures
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| 基金项目 |
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| 页码 |
1435-1438 |
马素青*.
丙戊酸钠、拉莫三嗪联合心理干预对癫痫患儿认知功能、生活质量及心理状况的影响 [J].
国际精神病学杂志.
2023; 50; (6).
1435 - 1438.